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Site-specific acetylation mark on an essential chromatin-remodeling complex promotes resistance to replication stress.
Charles GM, Chen C, Shih SC, Collins SR, Beltrao P, Zhang X, Sharma T, Tan S, Burlingame AL, Krogan NJ, Madhani HD, Narlikar GJ. Charles GM, et al. Among authors: chen c. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10620-5. doi: 10.1073/pnas.1019735108. Epub 2011 Jun 14. Proc Natl Acad Sci U S A. 2011. PMID: 21673141 Free PMC article.
Stalled spliceosomes are a signal for RNAi-mediated genome defense.
Dumesic PA, Natarajan P, Chen C, Drinnenberg IA, Schiller BJ, Thompson J, Moresco JJ, Yates JR 3rd, Bartel DP, Madhani HD. Dumesic PA, et al. Among authors: chen c. Cell. 2013 Feb 28;152(5):957-68. doi: 10.1016/j.cell.2013.01.046. Epub 2013 Feb 14. Cell. 2013. PMID: 23415457 Free PMC article.
Tyrosine phosphatase SHP-2 mediates C-type lectin receptor-induced activation of the kinase Syk and anti-fungal TH17 responses.
Deng Z, Ma S, Zhou H, Zang A, Fang Y, Li T, Shi H, Liu M, Du M, Taylor PR, Zhu HH, Chen J, Meng G, Li F, Chen C, Zhang Y, Jia XM, Lin X, Zhang X, Pearlman E, Li X, Feng GS, Xiao H. Deng Z, et al. Among authors: chen j, chen c. Nat Immunol. 2015 Jun;16(6):642-52. doi: 10.1038/ni.3155. Epub 2015 Apr 27. Nat Immunol. 2015. PMID: 25915733 Free PMC article.
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