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Page 1
Liraglutide targets the gut microbiota and the intestinal immune system to regulate insulin secretion.
Charpentier J, Briand F, Lelouvier B, Servant F, Azalbert V, Puel A, Christensen JE, Waget A, Branchereau M, Garret C, Lluch J, Heymes C, Brousseau E, Burcelin R, Guzylack L, Sulpice T, Grasset E. Charpentier J, et al. Among authors: sulpice t. Acta Diabetol. 2021 Jul;58(7):881-897. doi: 10.1007/s00592-020-01657-8. Epub 2021 Mar 15. Acta Diabetol. 2021. PMID: 33723651
An adiponectin-like molecule with antidiabetic properties.
Sulpice T, Prunet-Marcassus B, Molveaux C, Cani PD, Vitte PA, Graber P, Dreano M, Burcelin R. Sulpice T, et al. Endocrinology. 2009 Oct;150(10):4493-501. doi: 10.1210/en.2008-1768. Epub 2009 Jul 16. Endocrinology. 2009. PMID: 19608652
CX3CR1 regulates gut microbiota and metabolism. A risk factor of type 2 diabetes.
Pomié C, Servant F, Garidou L, Azalbert V, Waget A, Klopp P, Garret C, Charpentier J, Briand F, Sulpice T, Lelouvier B, Douin-Echinard V, Burcelin R. Pomié C, et al. Among authors: sulpice t. Acta Diabetol. 2021 Aug;58(8):1035-1049. doi: 10.1007/s00592-021-01682-1. Epub 2021 Mar 22. Acta Diabetol. 2021. PMID: 33754166
Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment.
Amar J, Chabo C, Waget A, Klopp P, Vachoux C, Bermúdez-Humarán LG, Smirnova N, Bergé M, Sulpice T, Lahtinen S, Ouwehand A, Langella P, Rautonen N, Sansonetti PJ, Burcelin R. Amar J, et al. Among authors: sulpice t. EMBO Mol Med. 2011 Sep;3(9):559-72. doi: 10.1002/emmm.201100159. Epub 2011 Aug 3. EMBO Mol Med. 2011. PMID: 21735552 Free PMC article.
Metabolic endotoxemia initiates obesity and insulin resistance.
Cani PD, Amar J, Iglesias MA, Poggi M, Knauf C, Bastelica D, Neyrinck AM, Fava F, Tuohy KM, Chabo C, Waget A, Delmée E, Cousin B, Sulpice T, Chamontin B, Ferrières J, Tanti JF, Gibson GR, Casteilla L, Delzenne NM, Alessi MC, Burcelin R. Cani PD, et al. Among authors: sulpice t. Diabetes. 2007 Jul;56(7):1761-72. doi: 10.2337/db06-1491. Epub 2007 Apr 24. Diabetes. 2007. PMID: 17456850
Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass.
Girousse A, Tavernier G, Valle C, Moro C, Mejhert N, Dinel AL, Houssier M, Roussel B, Besse-Patin A, Combes M, Mir L, Monbrun L, Bézaire V, Prunet-Marcassus B, Waget A, Vila I, Caspar-Bauguil S, Louche K, Marques MA, Mairal A, Renoud ML, Galitzky J, Holm C, Mouisel E, Thalamas C, Viguerie N, Sulpice T, Burcelin R, Arner P, Langin D. Girousse A, et al. Among authors: sulpice t. PLoS Biol. 2013;11(2):e1001485. doi: 10.1371/journal.pbio.1001485. Epub 2013 Feb 19. PLoS Biol. 2013. PMID: 23431266 Free PMC article. Clinical Trial.
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