Demuth HU - Search Results

1

Structures of glycosylated mammalian glutaminyl cyclases reveal conformational variability near the active center.

Ruiz-Carrillo D, Koch B, Parthier C, Wermann M, Dambe T, Buchholz M, Ludwig HH, Heiser U, Rahfeld JU, Stubbs MT, Schilling S, Demuth HU. Ruiz-Carrillo D, et al. Among authors: demuth hu. Biochemistry. 2011 Jul 19;50(28):6280-8. doi: 10.1021/bi200249h. Epub 2011 Jun 27. Biochemistry. 2011. PMID: 21671571

2

Continuous spectrometric assays for glutaminyl cyclase activity.

Schilling S, Hoffmann T, Wermann M, Heiser U, Wasternack C, Demuth HU. Schilling S, et al. Among authors: demuth hu. Anal Biochem. 2002 Apr 1;303(1):49-56. doi: 10.1006/abio.2001.5560. Anal Biochem. 2002. PMID: 11906150

3

Heterologous expression and characterization of human glutaminyl cyclase: evidence for a disulfide bond with importance for catalytic activity.

Schilling S, Hoffmann T, Rosche F, Manhart S, Wasternack C, Demuth HU. Schilling S, et al. Among authors: demuth hu. Biochemistry. 2002 Sep 3;41(35):10849-57. doi: 10.1021/bi0260381. Biochemistry. 2002. PMID: 12196024

4

Substrate specificity of glutaminyl cyclases from plants and animals.

Schilling S, Manhart S, Hoffmann T, Ludwig HH, Wasternack C, Demuth HU. Schilling S, et al. Among authors: demuth hu. Biol Chem. 2003 Dec;384(12):1583-92. doi: 10.1515/BC.2003.175. Biol Chem. 2003. PMID: 14719800

5

Glutaminyl cyclases unfold glutamyl cyclase activity under mild acid conditions.

Schilling S, Hoffmann T, Manhart S, Hoffmann M, Demuth HU. Schilling S, et al. Among authors: demuth hu. FEBS Lett. 2004 Apr 9;563(1-3):191-6. doi: 10.1016/S0014-5793(04)00300-X. FEBS Lett. 2004. PMID: 15063747 Free article.

6

Isolation, catalytic properties, and competitive inhibitors of the zinc-dependent murine glutaminyl cyclase.

Schilling S, Cynis H, von Bohlen A, Hoffmann T, Wermann M, Heiser U, Buchholz M, Zunkel K, Demuth HU. Schilling S, et al. Among authors: demuth hu. Biochemistry. 2005 Oct 11;44(40):13415-24. doi: 10.1021/bi051142e. Biochemistry. 2005. PMID: 16201766

7

Inhibition of glutaminyl cyclase alters pyroglutamate formation in mammalian cells.

Cynis H, Schilling S, Bodnár M, Hoffmann T, Heiser U, Saido TC, Demuth HU. Cynis H, et al. Among authors: demuth hu. Biochim Biophys Acta. 2006 Oct;1764(10):1618-25. doi: 10.1016/j.bbapap.2006.08.003. Epub 2006 Aug 16. Biochim Biophys Acta. 2006. PMID: 17005457

8

Isolation and characterization of the glutaminyl cyclases from Solanum tuberosum and Arabidopsis thaliana: implications for physiological functions.

Schilling S, Stenzel I, von Bohlen A, Wermann M, Schulz K, Demuth HU, Wasternack C. Schilling S, et al. Among authors: demuth hu. Biol Chem. 2007 Feb;388(2):145-53. doi: 10.1515/BC.2007.016. Biol Chem. 2007. PMID: 17261077

9

Isolation and characterization of glutaminyl cyclases from Drosophila: evidence for enzyme forms with different subcellular localization.

Schilling S, Lindner C, Koch B, Wermann M, Rahfeld JU, von Bohlen A, Rudolph T, Reuter G, Demuth HU. Schilling S, et al. Among authors: demuth hu. Biochemistry. 2007 Sep 25;46(38):10921-30. doi: 10.1021/bi701043x. Epub 2007 Aug 28. Biochemistry. 2007. PMID: 17722885

10

Isolation of an isoenzyme of human glutaminyl cyclase: retention in the Golgi complex suggests involvement in the protein maturation machinery.

Cynis H, Rahfeld JU, Stephan A, Kehlen A, Koch B, Wermann M, Demuth HU, Schilling S. Cynis H, et al. Among authors: demuth hu. J Mol Biol. 2008 Jun 20;379(5):966-80. doi: 10.1016/j.jmb.2008.03.078. Epub 2008 Apr 15. J Mol Biol. 2008. PMID: 18486145

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