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Page 1
Carvedilol targets human K2P 3.1 (TASK1) K+ leak channels.
Staudacher K, Staudacher I, Ficker E, Seyler C, Gierten J, Kisselbach J, Rahm AK, Trappe K, Schweizer PA, Becker R, Katus HA, Thomas D. Staudacher K, et al. Among authors: kisselbach j. Br J Pharmacol. 2011 Jul;163(5):1099-110. doi: 10.1111/j.1476-5381.2011.01319.x. Br J Pharmacol. 2011. PMID: 21410455 Free PMC article.
PKC-dependent activation of human K(2P) 18.1 K(+) channels.
Rahm AK, Gierten J, Kisselbach J, Staudacher I, Staudacher K, Schweizer PA, Becker R, Katus HA, Thomas D. Rahm AK, et al. Among authors: kisselbach j. Br J Pharmacol. 2012 May;166(2):764-73. doi: 10.1111/j.1476-5381.2011.01813.x. Br J Pharmacol. 2012. PMID: 22168364 Free PMC article.
Mechanisms of zolpidem-induced long QT syndrome: acute inhibition of recombinant hERG K(+) channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells.
Jehle J, Ficker E, Wan X, Deschenes I, Kisselbach J, Wiedmann F, Staudacher I, Schmidt C, Schweizer PA, Becker R, Katus HA, Thomas D. Jehle J, et al. Among authors: kisselbach j. Br J Pharmacol. 2013 Mar;168(5):1215-29. doi: 10.1111/bph.12002. Br J Pharmacol. 2013. PMID: 23061993 Free PMC article.
Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine.
Obers S, Staudacher I, Ficker E, Dennis A, Koschny R, Erdal H, Bloehs R, Kisselbach J, Karle CA, Schweizer PA, Katus HA, Thomas D. Obers S, et al. Among authors: kisselbach j. Naunyn Schmiedebergs Arch Pharmacol. 2010 May;381(5):385-400. doi: 10.1007/s00210-010-0496-7. Epub 2010 Mar 13. Naunyn Schmiedebergs Arch Pharmacol. 2010. PMID: 20229012 Free article.
hERG K+ channel-associated cardiac effects of the antidepressant drug desipramine.
Staudacher I, Wang L, Wan X, Obers S, Wenzel W, Tristram F, Koschny R, Staudacher K, Kisselbach J, Koelsch P, Schweizer PA, Katus HA, Ficker E, Thomas D. Staudacher I, et al. Among authors: kisselbach j. Naunyn Schmiedebergs Arch Pharmacol. 2011 Feb;383(2):119-39. doi: 10.1007/s00210-010-0583-9. Epub 2010 Dec 1. Naunyn Schmiedebergs Arch Pharmacol. 2011. PMID: 21120454
12 results