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Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and Selective Urea FAAH Inhibitor.
ACS Med Chem Lett. 2011 Feb 10;2(2):91-96. doi: 10.1021/ml100190t.
ACS Med Chem Lett. 2011.
PMID: 21666860
Free PMC article.
Benzothiophene piperazine and piperidine urea inhibitors of fatty acid amide hydrolase (FAAH).
Johnson DS, Ahn K, Kesten S, Lazerwith SE, Song Y, Morris M, Fay L, Gregory T, Stiff C, Dunbar JB Jr, Liimatta M, Beidler D, Smith S, Nomanbhoy TK, Cravatt BF.
Johnson DS, et al.
Bioorg Med Chem Lett. 2009 May 15;19(10):2865-9. doi: 10.1016/j.bmcl.2009.03.080. Epub 2009 Mar 24.
Bioorg Med Chem Lett. 2009.
PMID: 19386497
Free PMC article.
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Discovery of PF-00217830: aryl piperazine napthyridinones as D2 partial agonists for schizophrenia and bipolar disorder.
Johnson DS, Choi C, Fay LK, Favor DA, Repine JT, White AD, Akunne HC, Fitzgerald L, Nicholls K, Snyder BJ, Whetzel SZ, Zhang L, Serpa KA.
Johnson DS, et al. Among authors: fay lk.
Bioorg Med Chem Lett. 2011 May 1;21(9):2621-5. doi: 10.1016/j.bmcl.2011.01.059. Epub 2011 Jan 22.
Bioorg Med Chem Lett. 2011.
PMID: 21353774
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Design, synthesis, and biological activity of novel polycyclic aza-amide FKBP12 ligands.
Hudack RA Jr, Barta NS, Guo C, Deal J, Dong L, Fay LK, Caprathe B, Chatterjee A, Vanderpool D, Bigge C, Showalter R, Bender S, Augelli-Szafran CE, Lunney E, Hou X.
Hudack RA Jr, et al. Among authors: fay lk.
J Med Chem. 2006 Feb 9;49(3):1202-6. doi: 10.1021/jm049161u.
J Med Chem. 2006.
PMID: 16451085
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