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Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models.
Cooper AA, Gitler AD, Cashikar A, Haynes CM, Hill KJ, Bhullar B, Liu K, Xu K, Strathearn KE, Liu F, Cao S, Caldwell KA, Caldwell GA, Marsischky G, Kolodner RD, Labaer J, Rochet JC, Bonini NM, Lindquist S. Cooper AA, et al. Among authors: gitler ad. Science. 2006 Jul 21;313(5785):324-8. doi: 10.1126/science.1129462. Epub 2006 Jun 22. Science. 2006. PMID: 16794039 Free PMC article.
Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS.
Elden AC, Kim HJ, Hart MP, Chen-Plotkin AS, Johnson BS, Fang X, Armakola M, Geser F, Greene R, Lu MM, Padmanabhan A, Clay-Falcone D, McCluskey L, Elman L, Juhr D, Gruber PJ, Rüb U, Auburger G, Trojanowski JQ, Lee VM, Van Deerlin VM, Bonini NM, Gitler AD. Elden AC, et al. Among authors: gitler ad. Nature. 2010 Aug 26;466(7310):1069-75. doi: 10.1038/nature09320. Nature. 2010. PMID: 20740007 Free PMC article.
TDP-43 toxicity in yeast.
Armakola M, Hart MP, Gitler AD. Armakola M, et al. Among authors: gitler ad. Methods. 2011 Mar;53(3):238-45. doi: 10.1016/j.ymeth.2010.11.006. Epub 2010 Nov 27. Methods. 2011. PMID: 21115123 Free PMC article. Review.
Ataxin-2 intermediate-length polyglutamine expansions in European ALS patients.
Lee T, Li YR, Ingre C, Weber M, Grehl T, Gredal O, de Carvalho M, Meyer T, Tysnes OB, Auburger G, Gispert S, Bonini NM, Andersen PM, Gitler AD. Lee T, et al. Among authors: gitler ad. Hum Mol Genet. 2011 May 1;20(9):1697-700. doi: 10.1093/hmg/ddr045. Epub 2011 Feb 3. Hum Mol Genet. 2011. PMID: 21292779 Free PMC article.
PolyQ repeat expansions in ATXN2 associated with ALS are CAA interrupted repeats.
Yu Z, Zhu Y, Chen-Plotkin AS, Clay-Falcone D, McCluskey L, Elman L, Kalb RG, Trojanowski JQ, Lee VM, Van Deerlin VM, Gitler AD, Bonini NM. Yu Z, et al. Among authors: gitler ad. PLoS One. 2011 Mar 29;6(3):e17951. doi: 10.1371/journal.pone.0017951. PLoS One. 2011. PMID: 21479228 Free PMC article.
173 results