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Increasing the clinical efficacy of NK and antibody-mediated cancer immunotherapy: potential predictors of successful clinical outcome based on observations in high-risk neuroblastoma.
Koehn TA, Trimble LL, Alderson KL, Erbe AK, McDowell KA, Grzywacz B, Hank JA, Sondel PM. Koehn TA, et al. Among authors: alderson kl. Front Pharmacol. 2012 May 16;3:91. doi: 10.3389/fphar.2012.00091. eCollection 2012. Front Pharmacol. 2012. PMID: 22623917 Free PMC article.
T-cell-independent antitumor effects of CD40 ligation.
Rakhmilevich AL, Alderson KL, Sondel PM. Rakhmilevich AL, et al. Among authors: alderson kl. Int Rev Immunol. 2012 Aug;31(4):267-78. doi: 10.3109/08830185.2012.698337. Int Rev Immunol. 2012. PMID: 22804571 Free PMC article. Review.
Intratumoral hu14.18-IL-2 (IC) induces local and systemic antitumor effects that involve both activated T and NK cells as well as enhanced IC retention.
Yang RK, Kalogriopoulos NA, Rakhmilevich AL, Ranheim EA, Seo S, Kim K, Alderson KL, Gan J, Reisfeld RA, Gillies SD, Hank JA, Sondel PM. Yang RK, et al. Among authors: alderson kl. J Immunol. 2012 Sep 1;189(5):2656-64. doi: 10.4049/jimmunol.1200934. Epub 2012 Jul 27. J Immunol. 2012. PMID: 22844125 Free PMC article.
Enhancement of the anti-melanoma response of Hu14.18K322A by αCD40 + CpG.
Alderson KL, Luangrath M, Elsenheimer MM, Gillies SD, Navid F, Rakhmilevich AL, Sondel PM. Alderson KL, et al. Cancer Immunol Immunother. 2013 Apr;62(4):665-75. doi: 10.1007/s00262-012-1372-8. Epub 2012 Nov 15. Cancer Immunol Immunother. 2013. PMID: 23151945 Free PMC article.
Intratumoral treatment of smaller mouse neuroblastoma tumors with a recombinant protein consisting of IL-2 linked to the hu14.18 antibody increases intratumoral CD8+ T and NK cells and improves survival.
Yang RK, Kalogriopoulos NA, Rakhmilevich AL, Ranheim EA, Seo S, Kim K, Alderson KL, Gan J, Reisfeld RA, Gillies SD, Hank JA, Sondel PM. Yang RK, et al. Among authors: alderson kl. Cancer Immunol Immunother. 2013 Aug;62(8):1303-13. doi: 10.1007/s00262-013-1430-x. Epub 2013 May 10. Cancer Immunol Immunother. 2013. PMID: 23661160 Free PMC article.
Delineation of antigen-specific and antigen-nonspecific CD8(+) memory T-cell responses after cytokine-based cancer immunotherapy.
Tietze JK, Wilkins DE, Sckisel GD, Bouchlaka MN, Alderson KL, Weiss JM, Ames E, Bruhn KW, Craft N, Wiltrout RH, Longo DL, Lanier LL, Blazar BR, Redelman D, Murphy WJ. Tietze JK, et al. Among authors: alderson kl. Blood. 2012 Mar 29;119(13):3073-83. doi: 10.1182/blood-2011-07-369736. Epub 2012 Jan 17. Blood. 2012. PMID: 22251483 Free PMC article.
14 results