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Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin.
Hoste E, Kemperman P, Devos M, Denecker G, Kezic S, Yau N, Gilbert B, Lippens S, De Groote P, Roelandt R, Van Damme P, Gevaert K, Presland RB, Takahara H, Puppels G, Caspers P, Vandenabeele P, Declercq W. Hoste E, et al. Among authors: gilbert b. J Invest Dermatol. 2011 Nov;131(11):2233-41. doi: 10.1038/jid.2011.153. Epub 2011 Jun 9. J Invest Dermatol. 2011. PMID: 21654840 Free article.
Keratinocyte-Specific Ablation of RIPK4 Allows Epidermal Cornification but Impairs Skin Barrier Formation.
Urwyler-Rösselet C, Tanghe G, Leurs K, Gilbert B, De Rycke R, De Bruyne M, Lippens S, Bartunkova S, De Groote P, Niessen C, Haftek M, Vandenabeele P, Declercq W. Urwyler-Rösselet C, et al. Among authors: gilbert b. J Invest Dermatol. 2018 Jun;138(6):1268-1278. doi: 10.1016/j.jid.2017.12.031. Epub 2018 Jan 6. J Invest Dermatol. 2018. PMID: 29317263 Free article.
Caspase-14 protects against epidermal UVB photodamage and water loss.
Denecker G, Hoste E, Gilbert B, Hochepied T, Ovaere P, Lippens S, Van den Broecke C, Van Damme P, D'Herde K, Hachem JP, Borgonie G, Presland RB, Schoonjans L, Libert C, Vandekerckhove J, Gevaert K, Vandenabeele P, Declercq W. Denecker G, et al. Among authors: gilbert b. Nat Cell Biol. 2007 Jun;9(6):666-74. doi: 10.1038/ncb1597. Epub 2007 May 21. Nat Cell Biol. 2007. PMID: 17515931
Filaggrin degradation by caspase-14 is required for UVB photoprotection but does not influence allergic sensitization in a mouse model of atopic dermatitis.
Devos M, Prawitt J, Staumont-Salle D, Hoste E, Fleury S, Bouchaert E, Gilbert B, Lippens S, Vandenabeele P, Dombrowicz D, Declercq W. Devos M, et al. Among authors: gilbert b. J Invest Dermatol. 2012 Dec;132(12):2857-60. doi: 10.1038/jid.2012.236. Epub 2012 Aug 30. J Invest Dermatol. 2012. PMID: 22931922 Free article. No abstract available.
Caspase-14-deficient mice are more prone to the development of parakeratosis.
Hoste E, Denecker G, Gilbert B, Van Nieuwerburgh F, van der Fits L, Asselbergh B, De Rycke R, Hachem JP, Deforce D, Prens EP, Vandenabeele P, Declercq W. Hoste E, et al. Among authors: gilbert b. J Invest Dermatol. 2013 Mar;133(3):742-750. doi: 10.1038/jid.2012.350. Epub 2012 Sep 27. J Invest Dermatol. 2013. PMID: 23014340 Free article.
Elevated ΔNp63α Levels Facilitate Epidermal and Biliary Oncogenic Transformation.
Devos M, Gilbert B, Denecker G, Leurs K, Mc Guire C, Lemeire K, Hochepied T, Vuylsteke M, Lambert J, Van Den Broecke C, Libbrecht L, Haigh J, Berx G, Lippens S, Vandenabeele P, Declercq W. Devos M, et al. Among authors: gilbert b. J Invest Dermatol. 2017 Feb;137(2):494-505. doi: 10.1016/j.jid.2016.09.026. Epub 2016 Oct 7. J Invest Dermatol. 2017. PMID: 27725202 Free article.
Keratinocyte Expression of A20/TNFAIP3 Controls Skin Inflammation Associated with Atopic Dermatitis and Psoriasis.
Devos M, Mogilenko DA, Fleury S, Gilbert B, Becquart C, Quemener S, Dehondt H, Tougaard P, Staels B, Bachert C, Vandenabeele P, Van Loo G, Staumont-Salle D, Declercq W, Dombrowicz D. Devos M, et al. Among authors: gilbert b. J Invest Dermatol. 2019 Jan;139(1):135-145. doi: 10.1016/j.jid.2018.06.191. Epub 2018 Aug 14. J Invest Dermatol. 2019. PMID: 30118730 Free article.
Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis.
Lippens S, Lefebvre S, Gilbert B, Sze M, Devos M, Verhelst K, Vereecke L, Mc Guire C, Guérin C, Vandenabeele P, Pasparakis M, Mikkola ML, Beyaert R, Declercq W, van Loo G. Lippens S, et al. Among authors: gilbert b. Cell Death Differ. 2011 Dec;18(12):1845-53. doi: 10.1038/cdd.2011.55. Epub 2011 May 13. Cell Death Differ. 2011. PMID: 21566665 Free PMC article.
957 results