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Splenic fibroblasts control marginal zone B cell movement and function via two distinct Notch2-dependent regulatory programs.
Allman A, Gaudette BT, Kelly S, Alouche N, Carrington LJ, Perkey E, Brandstadter JD, Outen R, Vanderbeck A, Lederer K, Zhou Y, Faryabi RB, Robertson TF, Burkhardt JK, Tikhonova A, Aifantis I, Scarpellino L, Koch U, Radtke F, Lütge M, De Martin A, Ludewig B, Tveriakhina L, Gossler A, Mosteiro L, Siebel CW, Gómez Atria D, Luther SA, Allman D, Maillard I. Allman A, et al. Among authors: allman d. Immunity. 2025 Jan 14;58(1):143-161.e8. doi: 10.1016/j.immuni.2024.12.003. Epub 2024 Dec 27. Immunity. 2025. PMID: 39731910
Human IL-6 fosters long-term engraftment of patient-derived disease-driving myeloma cells in immunodeficient mice.
Hasanali ZS, Garfall AL, Burzenski L, Shultz LD, Tang Y, Kadu S, Sheppard NC, Liu W, Dopkin D, Vogl DT, Cohen AD, Waxman AJ, Susanibar-Adaniya SP, Carroll M, Stadtmauer EA, Allman D. Hasanali ZS, et al. Among authors: allman d. JCI Insight. 2024 May 7;9(10):e177300. doi: 10.1172/jci.insight.177300. JCI Insight. 2024. PMID: 38713510 Free PMC article.
Bone marrow plasma cells require P2RX4 to sense extracellular ATP.
Ishikawa M, Hasanali ZS, Zhao Y, Das A, Lavaert M, Roman CJ, Londregan J, Allman D, Bhandoola A. Ishikawa M, et al. Among authors: allman d. Nature. 2024 Feb;626(8001):1102-1107. doi: 10.1038/s41586-024-07047-2. Epub 2024 Feb 14. Nature. 2024. PMID: 38355795 Free PMC article.
Human IL-6 fosters long-term engraftment of patient derived disease-driving myeloma cells in immunodeficient mice.
Hasanali ZS, Garfall AL, Burzenski L, Shultz LD, Tang Y, Kadu S, Sheppard NC, Dopkin D, Vogl DT, Cohen AD, Waxman AJ, Susanibar-Adaniya SP, Carroll M, Stadtmauer EA, Allman D. Hasanali ZS, et al. Among authors: allman d. bioRxiv [Preprint]. 2024 Jan 24:2024.01.21.576547. doi: 10.1101/2024.01.21.576547. bioRxiv. 2024. Update in: JCI Insight. 2024 May 7;9(10):e177300. doi: 10.1172/jci.insight.177300 PMID: 38328086 Free PMC article. Updated. Preprint.
Immunotherapy targeting B cells and long-lived plasma cells effectively eliminates pre-existing donor-specific allo-antibodies.
Zhang Z, Markmann C, Yu M, Agarwal D, Rostami S, Wang W, Liu C, Zhao H, Ochoa T, Parvathaneni K, Xu X, Li E, Gonzalez V, Khadka R, Hoffmann J, Knox JJ, Scholler J, Marcellus B, Allman D, Fraietta JA, Samelson-Jones B, Milone MC, Monos D, Garfall AL, Naji A, Bhoj VG. Zhang Z, et al. Among authors: allman d. Cell Rep Med. 2023 Dec 19;4(12):101336. doi: 10.1016/j.xcrm.2023.101336. Cell Rep Med. 2023. PMID: 38118406 Free PMC article.
Increased activity of IRE1 improves the clinical presentation of EAE.
Bracchi-Ricard V, Nguyen K, Ricci D, Gaudette B, Henao-Mejia J, Brambilla R, Martynyuk T, Gidalevitz T, Allman D, Bethea JR, Argon Y. Bracchi-Ricard V, et al. Among authors: allman d. FASEB J. 2023 Dec;37(12):e23283. doi: 10.1096/fj.202300769RR. FASEB J. 2023. PMID: 37983957 Free PMC article.
Expression of the transcription factor Klf6 by thymic epithelial cells is required for thymus development.
Malin J, Martinez-Ruiz GU, Zhao Y, Shissler SC, Cowan JE, Ding Y, Morales-Sanchez A, Ishikawa M, Lavaert M, Das A, Butcher D, Warner AC, Kallarakal M, Chen J, Kedei N, Kelly M, Brinster LR, Allman D, Bhandoola A. Malin J, et al. Among authors: allman d. Sci Adv. 2023 Nov 17;9(46):eadg8126. doi: 10.1126/sciadv.adg8126. Epub 2023 Nov 15. Sci Adv. 2023. PMID: 37967174 Free PMC article.
221 results