Irth H - Search Results

1

High temperature liquid chromatography hyphenated with ESI-MS and ICP-MS detection for the structural characterization and quantification of halogen containing drug metabolites.

de Vlieger JS, Giezen MJ, Falck D, Tump C, van Heuveln F, Giera M, Kool J, Lingeman H, Wieling J, Honing M, Irth H, Niessen WM. de Vlieger JS, et al. Among authors: irth h. Anal Chim Acta. 2011 Jul 18;698(1-2):69-76. doi: 10.1016/j.aca.2011.04.053. Epub 2011 May 5. Anal Chim Acta. 2011. PMID: 21645661

2

Microfractionation revisited: a 1536 well high resolution screening assay.

Giera M, Heus F, Janssen L, Kool J, Lingeman H, Irth H. Giera M, et al. Among authors: irth h. Anal Chem. 2009 Jul 1;81(13):5460-6. doi: 10.1021/ac900622b. Anal Chem. 2009. PMID: 19507859

3

Structural elucidation of biologically active neomycin N-octyl derivatives in a regioisomeric mixture by means of liquid chromatography/ion trap time-of-flight mass spectrometry.

Giera M, de Vlieger JS, Lingeman H, Irth H, Niessen WM. Giera M, et al. Among authors: irth h. Rapid Commun Mass Spectrom. 2010 May 30;24(10):1439-46. doi: 10.1002/rcm.4534. Rapid Commun Mass Spectrom. 2010. PMID: 20411583

4

Development of an online p38α mitogen-activated protein kinase binding assay and integration of LC-HR-MS.

Falck D, de Vlieger JS, Niessen WM, Kool J, Honing M, Giera M, Irth H. Falck D, et al. Among authors: irth h. Anal Bioanal Chem. 2010 Oct;398(4):1771-80. doi: 10.1007/s00216-010-4087-8. Epub 2010 Aug 22. Anal Bioanal Chem. 2010. PMID: 20730527 Free PMC article.

5

On-line electrochemistry-bioaffinity screening with parallel HR-LC-MS for the generation and characterization of modified p38α kinase inhibitors.

Falck D, de Vlieger JS, Giera M, Honing M, Irth H, Niessen WM, Kool J. Falck D, et al. Among authors: irth h. Anal Bioanal Chem. 2012 Apr;403(2):367-75. doi: 10.1007/s00216-011-5663-2. Epub 2012 Jan 8. Anal Bioanal Chem. 2012. PMID: 22227812 Free PMC article.

6

On-line coupling of high-performance liquid chromatography to a continuous-flow enzyme assay based on electrospray ionization mass spectrometry.

de Boer AR, Letzel T, van Elswijk DA, Lingeman H, Niessen WM, Irth H. de Boer AR, et al. Among authors: irth h. Anal Chem. 2004 Jun 1;76(11):3155-61. doi: 10.1021/ac035380w. Anal Chem. 2004. PMID: 15167796

7

A microfluidic-based enzymatic assay for bioactivity screening combined with capillary liquid chromatography and mass spectrometry.

de Boer AR, Bruyneel B, Krabbe JG, Lingeman H, Niessen WM, Irth H. de Boer AR, et al. Among authors: irth h. Lab Chip. 2005 Nov;5(11):1286-92. doi: 10.1039/b506559c. Epub 2005 Sep 22. Lab Chip. 2005. PMID: 16234953

8

Selective quantitative bioanalysis of proteins in biological fluids by on-line immunoaffinity chromatography-protein digestion-liquid chromatography-mass spectrometry.

Hoos JS, Sudergat H, Hoelck JP, Stahl M, de Vlieger JS, Niessen WM, Lingeman H, Irth H. Hoos JS, et al. Among authors: irth h. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Jan 18;830(2):262-9. doi: 10.1016/j.jchromb.2005.11.002. Epub 2005 Nov 28. J Chromatogr B Analyt Technol Biomed Life Sci. 2006. PMID: 16311081

9

High-temperature liquid chromatography coupled on-line to a continuous-flow biochemical screening assay with electrospray ionization mass spectrometric detection.

de Boer AR, Alcaide-Hidalgo JM, Krabbe JG, Kolkman J, van Emde Boas CN, Niessen WM, Lingeman H, Irth H. de Boer AR, et al. Among authors: irth h. Anal Chem. 2005 Dec 15;77(24):7894-900. doi: 10.1021/ac0510282. Anal Chem. 2005. PMID: 16351135

10

Automated detection of covalent adducts to human serum albumin by immunoaffinity chromatography, on-line solution phase digestion and liquid chromatography-mass spectrometry.

Hoos JS, Damsten MC, de Vlieger JS, Commandeur JN, Vermeulen NP, Niessen WM, Lingeman H, Irth H. Hoos JS, et al. Among authors: irth h. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Nov 15;859(2):147-56. doi: 10.1016/j.jchromb.2007.09.015. Epub 2007 Sep 19. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17913598

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