Roy A - Search Results

1

The University of Kansas High-Throughput Screening laboratory. Part I: meeting drug-discovery needs in the heartland of America with entrepreneurial flair.

McDonald PR, Roy A, Chaguturu R. McDonald PR, et al. Among authors: roy a. Future Med Chem. 2011 May;3(7):789-95. doi: 10.4155/fmc.11.36. Future Med Chem. 2011. PMID: 21644824 Free PMC article.

2

Open access high throughput drug discovery in the public domain: a Mount Everest in the making.

Roy A, McDonald PR, Sittampalam S, Chaguturu R. Roy A, et al. Curr Pharm Biotechnol. 2010 Nov;11(7):764-78. doi: 10.2174/138920110792927757. Curr Pharm Biotechnol. 2010. PMID: 20809896 Free PMC article. Review.

3

Patent review.

Roy A. Roy A. Comb Chem High Throughput Screen. 2011 May;14(4):303. doi: 10.2174/138620711795222473. Comb Chem High Throughput Screen. 2011. PMID: 21375500 Review.

4

Patent review.

Roy A, McGee JE. Roy A, et al. Comb Chem High Throughput Screen. 2011 Aug;14(7):642. doi: 10.2174/138620711796367210. Comb Chem High Throughput Screen. 2011. PMID: 21668408

5

The University of Kansas High-Throughput Screening Laboratory. Part II: enabling collaborative drug-discovery partnerships through cutting-edge screening technology.

McDonald PR, Roy A, Chaguturu R. McDonald PR, et al. Among authors: roy a. Future Med Chem. 2011 Jul;3(9):1101-10. doi: 10.4155/fmc.11.84. Future Med Chem. 2011. PMID: 21806374 Free PMC article.

6

Compound ranking based on a new mathematical measure of effectiveness using time course data from cell-based assays.

Diaz FJ, McDonald PR, Roy A, Taylor B, Price A, Hall J, Blagg BS, Chaguturu R. Diaz FJ, et al. Among authors: roy a. Comb Chem High Throughput Screen. 2013 Mar;16(3):168-79. doi: 10.2174/1386207311316030002. Comb Chem High Throughput Screen. 2013. PMID: 22934946 Free PMC article.

7

High throughput screening operations at the University of Kansas.

Roy A. Roy A. Comb Chem High Throughput Screen. 2014 May;17(4):387-93. doi: 10.2174/1386207317666140323200405. Comb Chem High Throughput Screen. 2014. PMID: 24661207 Free PMC article.

8

A cell-based high-throughput screen for novel chemical inducers of fetal hemoglobin for treatment of hemoglobinopathies.

Peterson KR, Costa FC, Fedosyuk H, Neades RY, Chazelle AM, Zelenchuk L, Fonteles AH, Dalal P, Roy A, Chaguturu R, Li B, Pace BS. Peterson KR, et al. Among authors: roy a. PLoS One. 2014 Sep 16;9(9):e107006. doi: 10.1371/journal.pone.0107006. eCollection 2014. PLoS One. 2014. PMID: 25225870 Free PMC article.

9

Expanding the results of a high throughput screen against an isochorismate-pyruvate lyase to enzymes of a similar scaffold or mechanism.

Meneely KM, Luo Q, Riley AP, Taylor B, Roy A, Stein RL, Prisinzano TE, Lamb AL. Meneely KM, et al. Among authors: roy a. Bioorg Med Chem. 2014 Nov 1;22(21):5961-9. doi: 10.1016/j.bmc.2014.09.010. Epub 2014 Sep 16. Bioorg Med Chem. 2014. PMID: 25282647 Free PMC article.

10

Identification and validation of novel small molecule disruptors of HuR-mRNA interaction.

Wu X, Lan L, Wilson DM, Marquez RT, Tsao WC, Gao P, Roy A, Turner BA, McDonald P, Tunge JA, Rogers SA, Dixon DA, Aubé J, Xu L. Wu X, et al. Among authors: roy a. ACS Chem Biol. 2015 Jun 19;10(6):1476-84. doi: 10.1021/cb500851u. Epub 2015 Mar 17. ACS Chem Biol. 2015. PMID: 25750985 Free PMC article.

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