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Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage.
Billiet L, De Cock L, Sanchez Sanchez G, Mayer RL, Goetgeluk G, De Munter S, Pille M, Ingels J, Jansen H, Weening K, Pascal E, Raes K, Bonte S, Kerre T, Vandamme N, Seurinck R, Roels J, Lavaert M, Van Nieuwerburgh F, Leclercq G, Taghon T, Impens F, Menten B, Vermijlen D, Vandekerckhove B. Billiet L, et al. Among authors: taghon t. J Exp Med. 2023 Jun 5;220(6):e20220942. doi: 10.1084/jem.20220942. Epub 2023 Mar 20. J Exp Med. 2023. PMID: 36939517 Free PMC article.
Identification and Purification of Human T Cell Precursors.
Van de Walle I, Lambrechts N, Derveeuw A, Lavaert M, Roels J, Taghon T. Van de Walle I, et al. Among authors: taghon t. Methods Mol Biol. 2023;2580:315-333. doi: 10.1007/978-1-0716-2740-2_20. Methods Mol Biol. 2023. PMID: 36374467
During their development, human T cells undergo similar genomic changes and pass through the same developmental checkpoints as developing thymocytes in the mouse. The difference between both species, however, is that some of these developmental stages are characterized by …
During their development, human T cells undergo similar genomic changes and pass through the same developmental checkpoints as develo …
Knocking Out CD70 Rescues CD70-Specific NanoCAR T Cells from Antigen-Induced Exhaustion.
De Munter S, Buhl JL, De Cock L, Van Parys A, Daneels W, Pascal E, Deseins L, Ingels J, Goetgeluk G, Jansen H, Billiet L, Pille M, Van Duyse J, Bonte S, Vandamme N, Van Dorpe J, Offner F, Leclercq G, Taghon T, Depla E, Tavernier J, Kerre T, Drost J, Vandekerckhove B. De Munter S, et al. Among authors: taghon t. Cancer Immunol Res. 2024 Sep 3;12(9):1236-1251. doi: 10.1158/2326-6066.CIR-23-0677. Cancer Immunol Res. 2024. PMID: 38874582
Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum.
Ingels J, De Cock L, Stevens D, Mayer RL, Théry F, Sanchez GS, Vermijlen D, Weening K, De Smet S, Lootens N, Brusseel M, Verstraete T, Buyle J, Van Houtte E, Devreker P, Heyns K, De Munter S, Van Lint S, Goetgeluk G, Bonte S, Billiet L, Pille M, Jansen H, Pascal E, Deseins L, Vantomme L, Verdonckt M, Roelandt R, Eekhout T, Vandamme N, Leclercq G, Taghon T, Kerre T, Vanommeslaeghe F, Dhondt A, Ferdinande L, Van Dorpe J, Desender L, De Ryck F, Vermassen F, Surmont V, Impens F, Menten B, Vermaelen K, Vandekerckhove B. Ingels J, et al. Among authors: taghon t. Cell Rep Med. 2024 May 21;5(5):101516. doi: 10.1016/j.xcrm.2024.101516. Epub 2024 Apr 15. Cell Rep Med. 2024. PMID: 38626769 Free PMC article. Clinical Trial.
TL1A and IL-18 synergy promotes GM-CSF-dependent thymic granulopoiesis in mice.
Ruiz Pérez M, Maueröder C, Steels W, Verstraeten B, Lameire S, Xie W, Wyckaert L, Huysentruyt J, Divert T, Roelandt R, Gonçalves A, De Rycke R, Ravichandran K, Lambrecht BN, Taghon T, Leclercq G, Vandenabeele P, Tougaard P. Ruiz Pérez M, et al. Among authors: taghon t. Cell Mol Immunol. 2024 Aug;21(8):807-825. doi: 10.1038/s41423-024-01180-8. Epub 2024 Jun 5. Cell Mol Immunol. 2024. PMID: 38839915 Free PMC article.
The Wiskott-Aldrich syndrome protein is required for positive selection during T-cell lineage differentiation.
Pille M, Avila J, Sanchez GS, Goetgeluk G, De Munter S, Jansen H, Billiet L, Weening K, Xue H, Bonte S, Ingels J, De Cock L, Pascal E, Deseins L, Kerre T, Taghon T, Leclercq G, Vermijlen D, Davis B, Vandekerckhove B. Pille M, et al. Among authors: taghon t. Front Immunol. 2023 Jun 7;14:1188099. doi: 10.3389/fimmu.2023.1188099. eCollection 2023. Front Immunol. 2023. PMID: 37350958 Free PMC article.
In Vitro Model Systems to Study Human T Cell Development.
Lambrechts N, Liang KL, Velghe I, Strubbe S, Dolens AC, Taghon T. Lambrechts N, et al. Among authors: taghon t. Methods Mol Biol. 2023;2580:335-354. doi: 10.1007/978-1-0716-2740-2_21. Methods Mol Biol. 2023. PMID: 36374468 Review.
Type 1 immunity enables neonatal thymic ILC1 production.
Tougaard P, Ruiz Pérez M, Steels W, Huysentruyt J, Verstraeten B, Vetters J, Divert T, Gonçalves A, Roelandt R, Takahashi N, Janssens S, Buus TB, Taghon T, Leclercq G, Vandenabeele P. Tougaard P, et al. Among authors: taghon t. Sci Adv. 2024 Jan 19;10(3):eadh5520. doi: 10.1126/sciadv.adh5520. Epub 2024 Jan 17. Sci Adv. 2024. PMID: 38232171 Free PMC article.
150 results