Conjugation of a peptide to an antibody engineered with free cysteines dramatically improves half-life and activity.
Camacho RC, You S, D'Aquino KE, Li W, Wang Y, Gunnet J, Littrell J, Qi JS, Kang L, Jian W, MacDonald M, Tat T, Steiner D, Zhang YM, Lanter J, Patch R, Zhang R, Li J, Edavettal S, Edwards W, Dinh T, Wang LY, Connor J, Hunter M, Chi E, Swanson RV, Leonard JN, Case MA.
Camacho RC, et al. Among authors: d aquino ke, steiner d.
MAbs. 2020 Jan-Dec;12(1):1794687. doi: 10.1080/19420862.2020.1794687.
MAbs. 2020.
PMID: 32744157
Free PMC article.