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Phase I dose-escalation study to determine the safety, pharmacokinetics and pharmacodynamics of brivanib alaninate in combination with full-dose cetuximab in patients with advanced gastrointestinal malignancies who have failed prior therapy.
Garrett CR, Siu LL, El-Khoueiry A, Buter J, Rocha-Lima CM, Marshall J, LoRusso P, Major P, Chemidlin J, Mokliatchouk O, Velasquez L, Hayes W, Feltquate D, Syed S, Ford S, Kollia G, Galbraith S, Nuyten DS. Garrett CR, et al. Among authors: major p. Br J Cancer. 2011 Jun 28;105(1):44-52. doi: 10.1038/bjc.2011.182. Epub 2011 May 31. Br J Cancer. 2011. PMID: 21629245 Free PMC article. Clinical Trial.
A multicenter, randomized, open-label study to assess the steady-state pharmacokinetics of bevacizumab given with either XELOX or FOLFOX-4 in patients with metastatic colorectal cancer.
Zhi J, Chen E, Major P, Burns I, Robinson B, McKendrick J, Rittweger K, Abt M, Goldstein D. Zhi J, et al. Among authors: major p. Cancer Chemother Pharmacol. 2011 Nov;68(5):1199-206. doi: 10.1007/s00280-011-1606-z. Epub 2011 Mar 16. Cancer Chemother Pharmacol. 2011. PMID: 21409383 Clinical Trial.
1,024 results