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14-3-3sigma regulates B-cell homeostasis through stabilization of FOXO1.
Su YW, Hao Z, Hirao A, Yamamoto K, Lin WJ, Young A, Duncan GS, Yoshida H, Wakeham A, Lang PA, Murakami K, Hermeking H, Vogelstein B, Ohashi P, Mak TW. Su YW, et al. Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1555-60. doi: 10.1073/pnas.1017729108. Epub 2011 Jan 4. Proc Natl Acad Sci U S A. 2011. PMID: 21205887 Free PMC article.
IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology.
Pellegrini M, Calzascia T, Toe JG, Preston SP, Lin AE, Elford AR, Shahinian A, Lang PA, Lang KS, Morre M, Assouline B, Lahl K, Sparwasser T, Tedder TF, Paik JH, DePinho RA, Basta S, Ohashi PS, Mak TW. Pellegrini M, et al. Among authors: mak tw. Cell. 2011 Feb 18;144(4):601-13. doi: 10.1016/j.cell.2011.01.011. Epub 2011 Feb 3. Cell. 2011. PMID: 21295337 Free article.
Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity.
Lang PA, Lang KS, Xu HC, Grusdat M, Parish IA, Recher M, Elford AR, Dhanji S, Shaabani N, Tran CW, Dissanayake D, Rahbar R, Ghazarian M, Brüstle A, Fine J, Chen P, Weaver CT, Klose C, Diefenbach A, Häussinger D, Carlyle JR, Kaech SM, Mak TW, Ohashi PS. Lang PA, et al. Among authors: mak tw. Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1210-5. doi: 10.1073/pnas.1118834109. Epub 2011 Dec 13. Proc Natl Acad Sci U S A. 2012. PMID: 22167808 Free PMC article.
Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiency.
Lang PA, Shaabani N, Borkens S, Honke N, Scheu S, Booth S, Brenner D, Meryk A, Barthuber C, Recher M, Mak TW, Ohashi PS, Häussinger D, Griffiths GM, Thrasher AJ, Bouma G, Lang KS. Lang PA, et al. J Allergy Clin Immunol. 2013 Mar;131(3):815-24. doi: 10.1016/j.jaci.2012.08.050. Epub 2012 Nov 6. J Allergy Clin Immunol. 2013. PMID: 23141740 Free PMC article.
iRHOM2 is a critical pathogenic mediator of inflammatory arthritis.
Issuree PD, Maretzky T, McIlwain DR, Monette S, Qing X, Lang PA, Swendeman SL, Park-Min KH, Binder N, Kalliolias GD, Yarilina A, Horiuchi K, Ivashkiv LB, Mak TW, Salmon JE, Blobel CP. Issuree PD, et al. Among authors: mak tw. J Clin Invest. 2013 Feb;123(2):928-32. doi: 10.1172/JCI66168. Epub 2013 Jan 25. J Clin Invest. 2013. PMID: 23348744 Free PMC article.
Involvement of Toso in activation of monocytes, macrophages, and granulocytes.
Lang KS, Lang PA, Meryk A, Pandyra AA, Boucher LM, Pozdeev VI, Tusche MW, Göthert JR, Haight J, Wakeham A, You-Ten AJ, McIlwain DR, Merches K, Khairnar V, Recher M, Nolan GP, Hitoshi Y, Funkner P, Navarini AA, Verschoor A, Shaabani N, Honke N, Penn LZ, Ohashi PS, Häussinger D, Lee KH, Mak TW. Lang KS, et al. Proc Natl Acad Sci U S A. 2013 Feb 12;110(7):2593-8. doi: 10.1073/pnas.1222264110. Epub 2013 Jan 28. Proc Natl Acad Sci U S A. 2013. PMID: 23359703 Free PMC article.
1,618 results