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Insulin growth factor-2 binding protein 3 (IGF2BP3) is a glioblastoma-specific marker that activates phosphatidylinositol 3-kinase/mitogen-activated protein kinase (PI3K/MAPK) pathways by modulating IGF-2.
Suvasini R, Shruti B, Thota B, Shinde SV, Friedmann-Morvinski D, Nawaz Z, Prasanna KV, Thennarasu K, Hegde AS, Arivazhagan A, Chandramouli BA, Santosh V, Somasundaram K. Suvasini R, et al. J Biol Chem. 2011 Jul 22;286(29):25882-90. doi: 10.1074/jbc.M110.178012. Epub 2011 May 25. J Biol Chem. 2011. PMID: 21613208 Free PMC article.