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Targeting the hepatitis B cccDNA with a sequence-specific ARCUS nuclease to eliminate hepatitis B virus in vivo.
Gorsuch CL, Nemec P, Yu M, Xu S, Han D, Smith J, Lape J, van Buuren N, Ramirez R, Muench RC, Holdorf MM, Feierbach B, Falls G, Holt J, Shoop W, Sevigny E, Karriker F, Brown RV, Joshi A, Goodwin T, Tam YK, Lin PJC, Semple SC, Leatherbury N, Delaney Iv WE, Jantz D, Rhoden Smith A. Gorsuch CL, et al. Among authors: brown rv. Mol Ther. 2022 Sep 7;30(9):2909-2922. doi: 10.1016/j.ymthe.2022.05.013. Epub 2022 May 16. Mol Ther. 2022. PMID: 35581938 Free PMC article.
Impacto - A single-arm open-label pilot trial of a digital-based integrated smoking cessation program for Spanish-speaking Hispanic individuals who smoke: Development, feasibility, engagement, and clinical outcomes.
Zvolensky MJ, Brown RA, Shepherd JM, Brown JT, Redmond BY, Alcocer S. Zvolensky MJ, et al. Among authors: brown ra. J Subst Use Addict Treat. 2025 Jan 24:209632. doi: 10.1016/j.josat.2025.209632. Online ahead of print. J Subst Use Addict Treat. 2025. PMID: 39864556
Characteristics of children and adolescents with multidrug-resistant and rifampicin-resistant tuberculosis and their association with treatment outcomes: a systematic review and individual participant data meta-analysis.
Garcia-Prats AJ, Garcia-Cremades M, Cox V, Kredo T, Dunbar R, Schaaf HS, Seddon JA, Furin J, Achar J, Radke K, Sachs T, Abubakirov A, Ahmed S, Akkerman OW, Al Ani NA, Amanullah F, Ahmad N, Anderson LF, Asfaw M, Bango F, Bauer T, Becerra M, Boeree M, Brinkmann F, Brown R, Brust J, Campbell JR, Carvalho AC, Carvalho I, Cegielski JP, Centis R, Chan ED, Chauhan S, Chiang SS, Chan PC, D'Ambrosio L, Dalcolmo M, Daneilyan N, de Vries G, Draper HR; endTB Study Group; Fairlie L, Francis JR, Franke M, Gegia M, Restrepo CG, Guenther A, Gureva T, Haecker B, Harausz E, Hewison C, Hicks RM, Huerga H, Hughes J, Isaakidis P, Kadri SM, Khan MA, Kotrikadze T, Kuksa L, Lachenal N, Lange C, Lecca L, Lopez-Varela E, Lucena S, Mariandyshev A, Mattoo S, Mendez-Echevarria A, Migliori GB, Mitnick C, Mohr-Holland E, Mulanda W, Murzabakova T, Myrzalieve B, Ndjeka N, Niemann S, Ozere I, Padayatchi N, Parmar M, Parpieva N, Manzur-Ul-Alam M, Rybak N, Sachdeva KS, Salmon K, Santiago-Garcia B, Schaub D, Shah I, Shah S, Shah V, Sharma S, Shim TS, Shin S, Sinha A, Skrahina A, Solanki H, Solans BP, Soriano-Arandes A, Toktogonova A, van der Werf T, Velásquez GE, Williams B, Yim JJ, Savic R, Hesseling A. Garcia-Prats AJ, et al. Among authors: brown r. Lancet Child Adolesc Health. 2025 Feb;9(2):100-111. doi: 10.1016/S2352-4642(24)00330-4. Lancet Child Adolesc Health. 2025. PMID: 39855750
Serious Bacterial Infections and Hepatitis C Virus Among People Who Inject Drugs: A Syndemic or Intertwined Epidemics?
Stopka TJ, Nance RM, Mixson LS, Spencer H, Tsui JI, Leahy JM, Pho MT, DeJace J, Feinberg J, Young AM, Yang WT, Baltes A, Romo E, Brown RT, Nolte K, Miller WC, Zule WA, Jenkins WD, Delaney JA, Friedmann PD. Stopka TJ, et al. Among authors: brown rt. Trop Med Infect Dis. 2025 Jan 9;10(1):17. doi: 10.3390/tropicalmed10010017. Trop Med Infect Dis. 2025. PMID: 39852668 Free PMC article.
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