Lim WA - Search Results

1

Light control of plasma membrane recruitment using the Phy-PIF system.

Toettcher JE, Gong D, Lim WA, Weiner OD. Toettcher JE, et al. Among authors: lim wa. Methods Enzymol. 2011;497:409-23. doi: 10.1016/B978-0-12-385075-1.00017-2. Methods Enzymol. 2011. PMID: 21601096 Free PMC article.

2

Spatiotemporal control of cell signalling using a light-switchable protein interaction.

Levskaya A, Weiner OD, Lim WA, Voigt CA. Levskaya A, et al. Among authors: lim wa. Nature. 2009 Oct 15;461(7266):997-1001. doi: 10.1038/nature08446. Epub 2009 Sep 13. Nature. 2009. PMID: 19749742 Free PMC article.

3

The promise of optogenetics in cell biology: interrogating molecular circuits in space and time.

Toettcher JE, Voigt CA, Weiner OD, Lim WA. Toettcher JE, et al. Among authors: lim wa. Nat Methods. 2011 Jan;8(1):35-8. doi: 10.1038/nmeth.f.326. Epub 2010 Dec 20. Nat Methods. 2011. PMID: 21191370 Free PMC article.

4

Light-based feedback for controlling intracellular signaling dynamics.

Toettcher JE, Gong D, Lim WA, Weiner OD. Toettcher JE, et al. Among authors: lim wa. Nat Methods. 2011 Sep 11;8(10):837-9. doi: 10.1038/nmeth.1700. Nat Methods. 2011. PMID: 21909100 Free PMC article.

5

Actin dynamics rapidly reset chemoattractant receptor sensitivity following adaptation in neutrophils.

Dandekar SN, Park JS, Peng GE, Onuffer JJ, Lim WA, Weiner OD. Dandekar SN, et al. Among authors: lim wa. Philos Trans R Soc Lond B Biol Sci. 2013 Sep 23;368(1629):20130008. doi: 10.1098/rstb.2013.0008. Print 2013. Philos Trans R Soc Lond B Biol Sci. 2013. PMID: 24062580 Free PMC article.

6

Using optogenetics to interrogate the dynamic control of signal transmission by the Ras/Erk module.

Toettcher JE, Weiner OD, Lim WA. Toettcher JE, et al. Among authors: lim wa. Cell. 2013 Dec 5;155(6):1422-34. doi: 10.1016/j.cell.2013.11.004. Cell. 2013. PMID: 24315106 Free PMC article.

7

Synthetic control of mammalian-cell motility by engineering chemotaxis to an orthogonal bioinert chemical signal.

Park JS, Rhau B, Hermann A, McNally KA, Zhou C, Gong D, Weiner OD, Conklin BR, Onuffer J, Lim WA. Park JS, et al. Among authors: lim wa. Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):5896-901. doi: 10.1073/pnas.1402087111. Epub 2014 Apr 7. Proc Natl Acad Sci U S A. 2014. PMID: 24711398 Free PMC article.

8

Engineering dynamical control of cell fate switching using synthetic phospho-regulons.

Gordley RM, Williams RE, Bashor CJ, Toettcher JE, Yan S, Lim WA. Gordley RM, et al. Among authors: lim wa. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):13528-13533. doi: 10.1073/pnas.1610973113. Epub 2016 Nov 7. Proc Natl Acad Sci U S A. 2016. PMID: 27821768 Free PMC article.

9

Tracing Information Flow from Erk to Target Gene Induction Reveals Mechanisms of Dynamic and Combinatorial Control.

Wilson MZ, Ravindran PT, Lim WA, Toettcher JE. Wilson MZ, et al. Among authors: lim wa. Mol Cell. 2017 Sep 7;67(5):757-769.e5. doi: 10.1016/j.molcel.2017.07.016. Epub 2017 Aug 17. Mol Cell. 2017. PMID: 28826673 Free PMC article.

10

Cancer mutations and targeted drugs can disrupt dynamic signal encoding by the Ras-Erk pathway.

Bugaj LJ, Sabnis AJ, Mitchell A, Garbarino JE, Toettcher JE, Bivona TG, Lim WA. Bugaj LJ, et al. Among authors: lim wa. Science. 2018 Aug 31;361(6405):eaao3048. doi: 10.1126/science.aao3048. Science. 2018. PMID: 30166458 Free PMC article.

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