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Ongoing Dll4-Notch signaling is required for T-cell homeostasis in the adult thymus.
Billiard F, Kirshner JR, Tait M, Danave A, Taheri S, Zhang W, Waite JC, Olson K, Chen G, Coetzee S, Hylton D, Murphy AJ, Yancopoulos GD, Thurston G, Skokos D. Billiard F, et al. Among authors: chen g. Eur J Immunol. 2011 Aug;41(8):2207-16. doi: 10.1002/eji.201041343. Epub 2011 Jul 4. Eur J Immunol. 2011. PMID: 21598246 Free article.
Notch signaling drives intestinal graft-versus-host disease in mice and nonhuman primates.
Tkachev V, Vanderbeck A, Perkey E, Furlan SN, McGuckin C, Gómez Atria D, Gerdemann U, Rui X, Lane J, Hunt DJ, Zheng H, Colonna L, Hoffman M, Yu A, Outen R, Kelly S, Allman A, Koch U, Radtke F, Ludewig B, Burbach B, Shimizu Y, Panoskaltsis-Mortari A, Chen G, Carpenter SM, Harari O, Kuhnert F, Thurston G, Blazar BR, Kean LS, Maillard I. Tkachev V, et al. Among authors: chen g. Sci Transl Med. 2023 Jun 28;15(702):eadd1175. doi: 10.1126/scitranslmed.add1175. Epub 2023 Jun 28. Sci Transl Med. 2023. PMID: 37379368 Free PMC article.
Microenvironment-dependent growth of Sezary cells in humanized IL-15 mice.
Gao J, Ren S, Choonoo G, Chen G, Frleta D, Zhong J, Gupta N, Sharma P, Oyejide A, Atwal GS, Macdonald L, Murphy A, Kuhnert F. Gao J, et al. Among authors: chen g. Dis Model Mech. 2023 Oct 1;16(10):dmm050190. doi: 10.1242/dmm.050190. Epub 2023 Oct 13. Dis Model Mech. 2023. PMID: 37718909 Free PMC article.
Igf1r as a therapeutic target in a mouse model of basal-like breast cancer.
Klinakis A, Szabolcs M, Chen G, Xuan S, Hibshoosh H, Efstratiadis A. Klinakis A, et al. Among authors: chen g. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2359-64. doi: 10.1073/pnas.0810221106. Epub 2009 Jan 27. Proc Natl Acad Sci U S A. 2009. PMID: 19174523 Free PMC article.
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