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Elevated insulin-like growth factor 1 receptor signaling induces antiestrogen resistance through the MAPK/ERK and PI3K/Akt signaling routes.
Breast Cancer Res. 2011 May 19;13(3):R52. doi: 10.1186/bcr2883.
Breast Cancer Res. 2011.
PMID: 21595894
Free PMC article.
Epidermal growth factor receptor signalling in human breast cancer cells operates parallel to estrogen receptor α signalling and results in tamoxifen insensitive proliferation.
Moerkens M, Zhang Y, Wester L, van de Water B, Meerman JH.
Moerkens M, et al.
BMC Cancer. 2014 Apr 23;14:283. doi: 10.1186/1471-2407-14-283.
BMC Cancer. 2014.
PMID: 24758408
Free PMC article.
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IGF1R signaling drives antiestrogen resistance through PAK2/PIX activation in luminal breast cancer.
Zhang Y, Wester L, He J, Geiger T, Moerkens M, Siddappa R, Helmijr JA, Timmermans MM, Look MP, van Deurzen CHM, Martens JWM, Pont C, de Graauw M, Danen EHJ, Berns EMJJ, Meerman JHN, Jansen MPHM, van de Water B.
Zhang Y, et al. Among authors: moerkens m.
Oncogene. 2018 Apr;37(14):1869-1884. doi: 10.1038/s41388-017-0027-9. Epub 2018 Jan 22.
Oncogene. 2018.
PMID: 29353882
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2D and 3D assessment of neuropathology in rat brain after prenatal exposure to methylazoxymethanol, a model for developmental neurotoxicty.
de Groot DM, Hartgring S, van de Horst L, Moerkens M, Otto M, Bos-Kuijpers MH, Kaufmann WS, Lammers JH, O'callaghan JP, Waalkens-Berendsen ID, Pakkenberg B, Gundersen HG.
de Groot DM, et al. Among authors: moerkens m.
Reprod Toxicol. 2005 Sep-Oct;20(3):417-32. doi: 10.1016/j.reprotox.2005.04.006.
Reprod Toxicol. 2005.
PMID: 15964739
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