Connor-Robson N - Search Results

1

Functional alterations to the nigrostriatal system in mice lacking all three members of the synuclein family.

Anwar S, Peters O, Millership S, Ninkina N, Doig N, Connor-Robson N, Threlfell S, Kooner G, Deacon RM, Bannerman DM, Bolam JP, Chandra SS, Cragg SJ, Wade-Martins R, Buchman VL. Anwar S, et al. J Neurosci. 2011 May 18;31(20):7264-74. doi: 10.1523/JNEUROSCI.6194-10.2011. J Neurosci. 2011. PMID: 21593311 Free PMC article.

2

Chronic administration of dimebon ameliorates pathology in TauP301S transgenic mice.

Peters OM, Connor-Robson N, Sokolov VB, Aksinenko AY, Kukharsky MS, Bachurin SO, Ninkina N, Buchman VL. Peters OM, et al. J Alzheimers Dis. 2013;33(4):1041-9. doi: 10.3233/JAD-2012-121732. J Alzheimers Dis. 2013. PMID: 23099813

3

Contrasting effects of α-synuclein and γ-synuclein on the phenotype of cysteine string protein α (CSPα) null mutant mice suggest distinct function of these proteins in neuronal synapses.

Ninkina N, Peters OM, Connor-Robson N, Lytkina O, Sharfeddin E, Buchman VL. Ninkina N, et al. J Biol Chem. 2012 Dec 28;287(53):44471-7. doi: 10.1074/jbc.M112.422402. Epub 2012 Nov 5. J Biol Chem. 2012. PMID: 23129765 Free PMC article.

4

Simultaneous and independent detection of C9ORF72 alleles with low and high number of GGGGCC repeats using an optimised protocol of Southern blot hybridisation.

Buchman VL, Cooper-Knock J, Connor-Robson N, Higginbottom A, Kirby J, Razinskaya OD, Ninkina N, Shaw PJ. Buchman VL, et al. Mol Neurodegener. 2013 Apr 8;8:12. doi: 10.1186/1750-1326-8-12. Mol Neurodegener. 2013. PMID: 23566336 Free PMC article.

5

Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice.

Shelkovnikova TA, Peters OM, Deykin AV, Connor-Robson N, Robinson H, Ustyugov AA, Bachurin SO, Ermolkevich TG, Goldman IL, Sadchikova ER, Kovrazhkina EA, Skvortsova VI, Ling SC, Da Cruz S, Parone PA, Buchman VL, Ninkina NN. Shelkovnikova TA, et al. J Biol Chem. 2013 Aug 30;288(35):25266-25274. doi: 10.1074/jbc.M113.492017. Epub 2013 Jul 18. J Biol Chem. 2013. PMID: 23867462 Free PMC article.

6

Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasm.

Shelkovnikova TA, Robinson HK, Connor-Robson N, Buchman VL. Shelkovnikova TA, et al. Cell Cycle. 2013 Oct 1;12(19):3194-202. doi: 10.4161/cc.26241. Epub 2013 Sep 4. Cell Cycle. 2013. PMID: 24013423 Free PMC article.

7

A novel resource for studying function and dysfunction of α-synuclein: mouse lines for modulation of endogenous Snca gene expression.

Ninkina N, Connor-Robson N, Ustyugov AA, Tarasova TV, Shelkovnikova TA, Buchman VL. Ninkina N, et al. Sci Rep. 2015 Nov 13;5:16615. doi: 10.1038/srep16615. Sci Rep. 2015. PMID: 26564109 Free PMC article.

8

LRRK2 BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit function.

Sloan M, Alegre-Abarrategui J, Potgieter D, Kaufmann AK, Exley R, Deltheil T, Threlfell S, Connor-Robson N, Brimblecombe K, Wallings R, Cioroch M, Bannerman DM, Bolam JP, Magill PJ, Cragg SJ, Dodson PD, Wade-Martins R. Sloan M, et al. Hum Mol Genet. 2016 Mar 1;25(5):951-63. doi: 10.1093/hmg/ddv628. Epub 2016 Jan 6. Hum Mol Genet. 2016. PMID: 26744332 Free PMC article.

9

Combinational losses of synucleins reveal their differential requirements for compensating age-dependent alterations in motor behavior and dopamine metabolism.

Connor-Robson N, Peters OM, Millership S, Ninkina N, Buchman VL. Connor-Robson N, et al. Neurobiol Aging. 2016 Oct;46:107-12. doi: 10.1016/j.neurobiolaging.2016.06.020. Epub 2016 Jul 4. Neurobiol Aging. 2016. PMID: 27614017 Free PMC article.

10

Are rodent models of Parkinson's disease behaving as they should?

Vingill S, Connor-Robson N, Wade-Martins R. Vingill S, et al. Behav Brain Res. 2018 Oct 15;352:133-141. doi: 10.1016/j.bbr.2017.10.021. Epub 2017 Oct 24. Behav Brain Res. 2018. PMID: 29074404 Review.

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