West J - Search Results

1

Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators.

Owens P, Pickup MW, Novitskiy SV, Chytil A, Gorska AE, Aakre ME, West J, Moses HL. Owens P, et al. Among authors: west j. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2814-9. doi: 10.1073/pnas.1101139108. Epub 2011 May 16. Proc Natl Acad Sci U S A. 2012. PMID: 21576484 Free PMC article.

2

Physiologic and molecular consequences of endothelial Bmpr2 mutation.

Majka S, Hagen M, Blackwell T, Harral J, Johnson JA, Gendron R, Paradis H, Crona D, Loyd JE, Nozik-Grayck E, Stenmark KR, West J. Majka S, et al. Among authors: west j. Respir Res. 2011 Jun 22;12(1):84. doi: 10.1186/1465-9921-12-84. Respir Res. 2011. PMID: 21696628 Free PMC article.

3

Rescuing the BMPR2 signaling axis in pulmonary arterial hypertension.

West J, Austin E, Fessel JP, Loyd J, Hamid R. West J, et al. Drug Discov Today. 2014 Aug;19(8):1241-5. doi: 10.1016/j.drudis.2014.04.015. Epub 2014 May 2. Drug Discov Today. 2014. PMID: 24794464 Free PMC article. Review.

4

Pulmonary Vascular Platform Models the Effects of Flow and Pressure on Endothelial Dysfunction in BMPR2 Associated Pulmonary Arterial Hypertension.

D'Amico RW, Faley S, Shim HN, Prosser JR, Agrawal V, Bellan LM, West JD. D'Amico RW, et al. Int J Mol Sci. 2018 Aug 29;19(9):2561. doi: 10.3390/ijms19092561. Int J Mol Sci. 2018. PMID: 30158434 Free PMC article.

5

Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions.

West J, Harral J, Lane K, Deng Y, Ickes B, Crona D, Albu S, Stewart D, Fagan K. West J, et al. Am J Physiol Lung Cell Mol Physiol. 2008 Nov;295(5):L744-55. doi: 10.1152/ajplung.90255.2008. Epub 2008 Aug 22. Am J Physiol Lung Cell Mol Physiol. 2008. PMID: 18723761 Free PMC article.

6

Copy-number variation in BMPR2 is not associated with the pathogenesis of pulmonary arterial hypertension.

Johnson JA, Vnencak-Jones CL, Cogan JD, Loyd JE, West J. Johnson JA, et al. Among authors: west j. BMC Med Genet. 2009 Jun 16;10:58. doi: 10.1186/1471-2350-10-58. BMC Med Genet. 2009. PMID: 19531247 Free PMC article.

7

Cross talk between Smad, MAPK, and actin in the etiology of pulmonary arterial hypertension.

West J. West J. Adv Exp Med Biol. 2010;661:265-78. doi: 10.1007/978-1-60761-500-2_17. Adv Exp Med Biol. 2010. PMID: 20204736 Review.

8

BMPR2 mutation alters the lung macrophage endothelin-1 cascade in a mouse model and patients with heritable pulmonary artery hypertension.

Talati M, West J, Blackwell TR, Loyd JE, Meyrick B. Talati M, et al. Among authors: west j. Am J Physiol Lung Cell Mol Physiol. 2010 Sep;299(3):L363-73. doi: 10.1152/ajplung.00295.2009. Epub 2010 Jun 18. Am J Physiol Lung Cell Mol Physiol. 2010. PMID: 20562228 Free PMC article.

9

Oxidative injury is a common consequence of BMPR2 mutations.

Lane KL, Talati M, Austin E, Hemnes AR, Johnson JA, Fessel JP, Blackwell T, Mernaugh RL, Robinson L, Fike C, Roberts LJ 2nd, West J. Lane KL, et al. Among authors: west j. Pulm Circ. 2011;1(1):72-83. doi: 10.4103/2045-8932.78107. Pulm Circ. 2011. PMID: 21904662 Free PMC article.

10

Cytoskeletal defects in Bmpr2-associated pulmonary arterial hypertension.

Johnson JA, Hemnes AR, Perrien DS, Schuster M, Robinson LJ, Gladson S, Loibner H, Bai S, Blackwell TR, Tada Y, Harral JW, Talati M, Lane KB, Fagan KA, West J. Johnson JA, et al. Among authors: west j. Am J Physiol Lung Cell Mol Physiol. 2012 Mar 1;302(5):L474-84. doi: 10.1152/ajplung.00202.2011. Epub 2011 Dec 16. Am J Physiol Lung Cell Mol Physiol. 2012. PMID: 22180660 Free PMC article.

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