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A hormone-dependent module regulating energy balance.
Wang B, Moya N, Niessen S, Hoover H, Mihaylova MM, Shaw RJ, Yates JR 3rd, Fischer WH, Thomas JB, Montminy M. Wang B, et al. Among authors: shaw rj. Cell. 2011 May 13;145(4):596-606. doi: 10.1016/j.cell.2011.04.013. Cell. 2011. PMID: 21565616 Free PMC article.
Glucose metabolism and cancer.
Shaw RJ. Shaw RJ. Curr Opin Cell Biol. 2006 Dec;18(6):598-608. doi: 10.1016/j.ceb.2006.10.005. Epub 2006 Oct 12. Curr Opin Cell Biol. 2006. PMID: 17046224 Review.
AMPK phosphorylation of raptor mediates a metabolic checkpoint.
Gwinn DM, Shackelford DB, Egan DF, Mihaylova MM, Mery A, Vasquez DS, Turk BE, Shaw RJ. Gwinn DM, et al. Among authors: shaw rj. Mol Cell. 2008 Apr 25;30(2):214-26. doi: 10.1016/j.molcel.2008.03.003. Mol Cell. 2008. PMID: 18439900 Free PMC article.
AMPK and PPARdelta agonists are exercise mimetics.
Narkar VA, Downes M, Yu RT, Embler E, Wang YX, Banayo E, Mihaylova MM, Nelson MC, Zou Y, Juguilon H, Kang H, Shaw RJ, Evans RM. Narkar VA, et al. Among authors: shaw rj. Cell. 2008 Aug 8;134(3):405-15. doi: 10.1016/j.cell.2008.06.051. Epub 2008 Jul 31. Cell. 2008. PMID: 18674809 Free PMC article.
Raptor swoops in on metabolism.
Shaw RJ. Shaw RJ. Cell Metab. 2008 Nov;8(5):343-4. doi: 10.1016/j.cmet.2008.10.007. Cell Metab. 2008. PMID: 19046565 Free article.
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy.
Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, Mair W, Vasquez DS, Joshi A, Gwinn DM, Taylor R, Asara JM, Fitzpatrick J, Dillin A, Viollet B, Kundu M, Hansen M, Shaw RJ. Egan DF, et al. Among authors: shaw rj. Science. 2011 Jan 28;331(6016):456-61. doi: 10.1126/science.1196371. Epub 2010 Dec 23. Science. 2011. PMID: 21205641 Free PMC article.
553 results