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Page 1
Targeting superficial or nodular Basal cell carcinoma with topically formulated small molecule inhibitor of smoothened.
Tang T, Tang JY, Li D, Reich M, Callahan CA, Fu L, Yauch RL, Wang F, Kotkow K, Chang KS, Shpall E, Wu A, Rubin LL, Marsters JC Jr, Epstein EH Jr, Caro I, de Sauvage FJ. Tang T, et al. Among authors: de sauvage fj. Clin Cancer Res. 2011 May 15;17(10):3378-87. doi: 10.1158/1078-0432.CCR-10-3370. Epub 2011 May 10. Clin Cancer Res. 2011. PMID: 21558397 Free PMC article. Clinical Trial.
Activating Smoothened mutations in sporadic basal-cell carcinoma.
Xie J, Murone M, Luoh SM, Ryan A, Gu Q, Zhang C, Bonifas JM, Lam CW, Hynes M, Goddard A, Rosenthal A, Epstein EH Jr, de Sauvage FJ. Xie J, et al. Among authors: de sauvage fj. Nature. 1998 Jan 1;391(6662):90-2. doi: 10.1038/34201. Nature. 1998. PMID: 9422511
Activation of expression of hedgehog target genes in basal cell carcinomas.
Bonifas JM, Pennypacker S, Chuang PT, McMahon AP, Williams M, Rosenthal A, De Sauvage FJ, Epstein EH Jr. Bonifas JM, et al. Among authors: de sauvage fj. J Invest Dermatol. 2001 May;116(5):739-42. doi: 10.1046/j.1523-1747.2001.01315.x. J Invest Dermatol. 2001. PMID: 11348463 Free article.
The hedgehog signaling pathway in cancer.
Evangelista M, Tian H, de Sauvage FJ. Evangelista M, et al. Among authors: de sauvage fj. Clin Cancer Res. 2006 Oct 15;12(20 Pt 1):5924-8. doi: 10.1158/1078-0432.CCR-06-1736. Clin Cancer Res. 2006. PMID: 17062662 Review.
Targeting the Hedgehog pathway in cancer.
Rubin LL, de Sauvage FJ. Rubin LL, et al. Among authors: de sauvage fj. Nat Rev Drug Discov. 2006 Dec;5(12):1026-33. doi: 10.1038/nrd2086. Nat Rev Drug Discov. 2006. PMID: 17139287 Review.
A paracrine requirement for hedgehog signalling in cancer.
Yauch RL, Gould SE, Scales SJ, Tang T, Tian H, Ahn CP, Marshall D, Fu L, Januario T, Kallop D, Nannini-Pepe M, Kotkow K, Marsters JC, Rubin LL, de Sauvage FJ. Yauch RL, et al. Among authors: de sauvage fj. Nature. 2008 Sep 18;455(7211):406-10. doi: 10.1038/nature07275. Epub 2008 Aug 27. Nature. 2008. PMID: 18754008
Paracrine Hedgehog signaling in cancer.
Theunissen JW, de Sauvage FJ. Theunissen JW, et al. Among authors: de sauvage fj. Cancer Res. 2009 Aug 1;69(15):6007-10. doi: 10.1158/0008-5472.CAN-09-0756. Epub 2009 Jul 28. Cancer Res. 2009. PMID: 19638582 Review.
185 results