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Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation.
Isakoff MS, Sansam CG, Tamayo P, Subramanian A, Evans JA, Fillmore CM, Wang X, Biegel JA, Pomeroy SL, Mesirov JP, Roberts CW. Isakoff MS, et al. Among authors: subramanian a. Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17745-50. doi: 10.1073/pnas.0509014102. Epub 2005 Nov 21. Proc Natl Acad Sci U S A. 2005. PMID: 16301525 Free PMC article.
Perturbational profiling of nanomaterial biologic activity.
Shaw SY, Westly EC, Pittet MJ, Subramanian A, Schreiber SL, Weissleder R. Shaw SY, et al. Among authors: subramanian a. Proc Natl Acad Sci U S A. 2008 May 27;105(21):7387-92. doi: 10.1073/pnas.0802878105. Epub 2008 May 20. Proc Natl Acad Sci U S A. 2008. PMID: 18492802 Free PMC article.
Highly parallel identification of essential genes in cancer cells.
Luo B, Cheung HW, Subramanian A, Sharifnia T, Okamoto M, Yang X, Hinkle G, Boehm JS, Beroukhim R, Weir BA, Mermel C, Barbie DA, Awad T, Zhou X, Nguyen T, Piqani B, Li C, Golub TR, Meyerson M, Hacohen N, Hahn WC, Lander ES, Sabatini DM, Root DE. Luo B, et al. Among authors: subramanian a. Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20380-5. doi: 10.1073/pnas.0810485105. Epub 2008 Dec 17. Proc Natl Acad Sci U S A. 2008. PMID: 19091943 Free PMC article.
Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer.
Oliver TG, Mercer KL, Sayles LC, Burke JR, Mendus D, Lovejoy KS, Cheng MH, Subramanian A, Mu D, Powers S, Crowley D, Bronson RT, Whittaker CA, Bhutkar A, Lippard SJ, Golub T, Thomale J, Jacks T, Sweet-Cordero EA. Oliver TG, et al. Among authors: subramanian a. Genes Dev. 2010 Apr 15;24(8):837-52. doi: 10.1101/gad.1897010. Genes Dev. 2010. PMID: 20395368 Free PMC article.
Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling.
Wawer MJ, Li K, Gustafsdottir SM, Ljosa V, Bodycombe NE, Marton MA, Sokolnicki KL, Bray MA, Kemp MM, Winchester E, Taylor B, Grant GB, Hon CS, Duvall JR, Wilson JA, Bittker JA, Dančík V, Narayan R, Subramanian A, Winckler W, Golub TR, Carpenter AE, Shamji AF, Schreiber SL, Clemons PA. Wawer MJ, et al. Among authors: subramanian a. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):10911-6. doi: 10.1073/pnas.1410933111. Epub 2014 Jul 14. Proc Natl Acad Sci U S A. 2014. PMID: 25024206 Free PMC article.
Genetic modifiers of EGFR dependence in non-small cell lung cancer.
Sharifnia T, Rusu V, Piccioni F, Bagul M, Imielinski M, Cherniack AD, Pedamallu CS, Wong B, Wilson FH, Garraway LA, Altshuler D, Golub TR, Root DE, Subramanian A, Meyerson M. Sharifnia T, et al. Among authors: subramanian a. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18661-6. doi: 10.1073/pnas.1412228112. Epub 2014 Dec 15. Proc Natl Acad Sci U S A. 2014. PMID: 25512530 Free PMC article.
1,256 results