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Structural determination and tryptophan fluorescence of heterokaryon incompatibility C2 protein (HET-C2), a fungal glycolipid transfer protein (GLTP), provide novel insights into glycolipid specificity and membrane interaction by the GLTP fold.
Kenoth R, Simanshu DK, Kamlekar RK, Pike HM, Molotkovsky JG, Benson LM, Bergen HR 3rd, Prendergast FG, Malinina L, Venyaminov SY, Patel DJ, Brown RE. Kenoth R, et al. Among authors: malinina l. J Biol Chem. 2010 Apr 23;285(17):13066-78. doi: 10.1074/jbc.M109.093203. Epub 2010 Feb 17. J Biol Chem. 2010. PMID: 20164530 Free PMC article.
The glycolipid transfer protein (GLTP) domain of phosphoinositol 4-phosphate adaptor protein-2 (FAPP2): structure drives preference for simple neutral glycosphingolipids.
Kamlekar RK, Simanshu DK, Gao YG, Kenoth R, Pike HM, Prendergast FG, Malinina L, Molotkovsky JG, Venyaminov SY, Patel DJ, Brown RE. Kamlekar RK, et al. Among authors: malinina l. Biochim Biophys Acta. 2013 Feb;1831(2):417-27. doi: 10.1016/j.bbalip.2012.10.010. Epub 2012 Nov 16. Biochim Biophys Acta. 2013. PMID: 23159414 Free PMC article.
Sphingolipid transfer proteins defined by the GLTP-fold.
Malinina L, Simanshu DK, Zhai X, Samygina VR, Kamlekar R, Kenoth R, Ochoa-Lizarralde B, Malakhova ML, Molotkovsky JG, Patel DJ, Brown RE. Malinina L, et al. Q Rev Biophys. 2015 Aug;48(3):281-322. doi: 10.1017/S003358351400016X. Epub 2015 Mar 23. Q Rev Biophys. 2015. PMID: 25797198 Free PMC article.
Structural analyses of 4-phosphate adaptor protein 2 yield mechanistic insights into sphingolipid recognition by the glycolipid transfer protein family.
Ochoa-Lizarralde B, Gao YG, Popov AN, Samygina VR, Zhai X, Mishra SK, Boldyrev IA, Molotkovsky JG, Simanshu DK, Patel DJ, Brown RE, Malinina L. Ochoa-Lizarralde B, et al. Among authors: malinina l. J Biol Chem. 2018 Oct 26;293(43):16709-16723. doi: 10.1074/jbc.RA117.000733. Epub 2018 Sep 11. J Biol Chem. 2018. PMID: 30206120 Free PMC article.
Point mutational analysis of the liganding site in human glycolipid transfer protein. Functionality of the complex.
Malakhova ML, Malinina L, Pike HM, Kanack AT, Patel DJ, Brown RE. Malakhova ML, et al. Among authors: malinina l. J Biol Chem. 2005 Jul 15;280(28):26312-20. doi: 10.1074/jbc.M500481200. Epub 2005 May 18. J Biol Chem. 2005. PMID: 15901739 Free PMC article.
Recent structural determinations of the apo- and glycolipid-liganded forms of human GLTP have provided the first insights into the molecular architecture of the protein and its glycolipid binding site (Malinina, L., Malakhova, M. L., Brown, R. E., and Patel, …
Recent structural determinations of the apo- and glycolipid-liganded forms of human GLTP have provided the first insights into the molecular …
165 results