Tong Y - Search Results

1

Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures.

Hakimi M, Selvanantham T, Swinton E, Padmore RF, Tong Y, Kabbach G, Venderova K, Girardin SE, Bulman DE, Scherzer CR, LaVoie MJ, Gris D, Park DS, Angel JB, Shen J, Philpott DJ, Schlossmacher MG. Hakimi M, et al. Among authors: tong y. J Neural Transm (Vienna). 2011 May;118(5):795-808. doi: 10.1007/s00702-011-0653-2. Epub 2011 May 7. J Neural Transm (Vienna). 2011. PMID: 21552986 Free PMC article.

2

LRRK2 regulates synaptic vesicle endocytosis.

Shin N, Jeong H, Kwon J, Heo HY, Kwon JJ, Yun HJ, Kim CH, Han BS, Tong Y, Shen J, Hatano T, Hattori N, Kim KS, Chang S, Seol W. Shin N, et al. Among authors: tong y. Exp Cell Res. 2008 Jun 10;314(10):2055-65. doi: 10.1016/j.yexcr.2008.02.015. Epub 2008 Mar 5. Exp Cell Res. 2008. PMID: 18445495

3

R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice.

Tong Y, Pisani A, Martella G, Karouani M, Yamaguchi H, Pothos EN, Shen J. Tong Y, et al. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14622-7. doi: 10.1073/pnas.0906334106. Epub 2009 Aug 10. Proc Natl Acad Sci U S A. 2009. PMID: 19667187 Free PMC article.

4

alpha-synuclein and LRRK2: partners in crime.

Tong Y, Shen J. Tong Y, et al. Neuron. 2009 Dec 24;64(6):771-3. doi: 10.1016/j.neuron.2009.12.017. Neuron. 2009. PMID: 20064381 Free PMC article.

5

Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice.

Tong Y, Yamaguchi H, Giaime E, Boyle S, Kopan R, Kelleher RJ 3rd, Shen J. Tong Y, et al. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9879-84. doi: 10.1073/pnas.1004676107. Epub 2010 May 10. Proc Natl Acad Sci U S A. 2010. PMID: 20457918 Free PMC article.

6

14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization.

Nichols RJ, Dzamko N, Morrice NA, Campbell DG, Deak M, Ordureau A, Macartney T, Tong Y, Shen J, Prescott AR, Alessi DR. Nichols RJ, et al. Among authors: tong y. Biochem J. 2010 Sep 15;430(3):393-404. doi: 10.1042/BJ20100483. Biochem J. 2010. PMID: 20642453 Free PMC article.

7

Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway.

Tong Y, Giaime E, Yamaguchi H, Ichimura T, Liu Y, Si H, Cai H, Bonventre JV, Shen J. Tong Y, et al. Mol Neurodegener. 2012 Jan 9;7:2. doi: 10.1186/1750-1326-7-2. Mol Neurodegener. 2012. PMID: 22230652 Free PMC article.

8

Genetic analysis of Parkinson's disease-linked leucine-rich repeat kinase 2.

Tong Y, Shen J. Tong Y, et al. Biochem Soc Trans. 2012 Oct;40(5):1042-6. doi: 10.1042/BST20120112. Biochem Soc Trans. 2012. PMID: 22988862 Free PMC article. Review.

9

Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice.

Giaime E, Tong Y, Wagner LK, Yuan Y, Huang G, Shen J. Giaime E, et al. Among authors: tong y. Neuron. 2017 Nov 15;96(4):796-807.e6. doi: 10.1016/j.neuron.2017.09.036. Epub 2017 Oct 19. Neuron. 2017. PMID: 29056298 Free PMC article.

10

Cell autonomous role of leucine-rich repeat kinase in protection of dopaminergic neuron survival.

Kang J, Huang G, Ma L, Tong Y, Shahapal A, Chen P, Shen J. Kang J, et al. Among authors: tong y. bioRxiv [Preprint]. 2024 Mar 7:2023.10.06.561293. doi: 10.1101/2023.10.06.561293. bioRxiv. 2024. Update in: Elife. 2024 Jun 10;12:RP92673. doi: 10.7554/eLife.92673 PMID: 37873418 Free PMC article. Updated. Preprint.

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