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Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures.
Hakimi M, Selvanantham T, Swinton E, Padmore RF, Tong Y, Kabbach G, Venderova K, Girardin SE, Bulman DE, Scherzer CR, LaVoie MJ, Gris D, Park DS, Angel JB, Shen J, Philpott DJ, Schlossmacher MG. Hakimi M, et al. Among authors: schlossmacher mg. J Neural Transm (Vienna). 2011 May;118(5):795-808. doi: 10.1007/s00702-011-0653-2. Epub 2011 May 7. J Neural Transm (Vienna). 2011. PMID: 21552986 Free PMC article.
Molecular markers of early Parkinson's disease based on gene expression in blood.
Scherzer CR, Eklund AC, Morse LJ, Liao Z, Locascio JJ, Fefer D, Schwarzschild MA, Schlossmacher MG, Hauser MA, Vance JM, Sudarsky LR, Standaert DG, Growdon JH, Jensen RV, Gullans SR. Scherzer CR, et al. Among authors: schlossmacher mg. Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):955-60. doi: 10.1073/pnas.0610204104. Epub 2007 Jan 10. Proc Natl Acad Sci U S A. 2007. PMID: 17215369 Free PMC article.
The effects of oxidative stress on parkin and other E3 ligases.
LaVoie MJ, Cortese GP, Ostaszewski BL, Schlossmacher MG. LaVoie MJ, et al. Among authors: schlossmacher mg. J Neurochem. 2007 Dec;103(6):2354-68. doi: 10.1111/j.1471-4159.2007.04911.x. Epub 2007 Sep 19. J Neurochem. 2007. PMID: 17883392 Free article.
GATA transcription factors directly regulate the Parkinson's disease-linked gene alpha-synuclein.
Scherzer CR, Grass JA, Liao Z, Pepivani I, Zheng B, Eklund AC, Ney PA, Ng J, McGoldrick M, Mollenhauer B, Bresnick EH, Schlossmacher MG. Scherzer CR, et al. Among authors: schlossmacher mg. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10907-12. doi: 10.1073/pnas.0802437105. Epub 2008 Jul 31. Proc Natl Acad Sci U S A. 2008. PMID: 18669654 Free PMC article.
α-Synuclein in human cerebrospinal fluid is principally derived from neurons of the central nervous system.
Mollenhauer B, Trautmann E, Otte B, Ng J, Spreer A, Lange P, Sixel-Döring F, Hakimi M, Vonsattel JP, Nussbaum R, Trenkwalder C, Schlossmacher MG. Mollenhauer B, et al. Among authors: schlossmacher mg. J Neural Transm (Vienna). 2012 Jul;119(7):739-46. doi: 10.1007/s00702-012-0784-0. Epub 2012 Mar 18. J Neural Transm (Vienna). 2012. PMID: 22426833 Free PMC article.
Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease.
Rousseaux MW, Marcogliese PC, Qu D, Hewitt SJ, Seang S, Kim RH, Slack RS, Schlossmacher MG, Lagace DC, Mak TW, Park DS. Rousseaux MW, et al. Among authors: schlossmacher mg. Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15918-23. doi: 10.1073/pnas.1205102109. Epub 2012 Sep 10. Proc Natl Acad Sci U S A. 2012. PMID: 23019375 Free PMC article.
99 results