McIntosh LP - Search Results

1

Genomic and biochemical insights into the specificity of ETS transcription factors.

Hollenhorst PC, McIntosh LP, Graves BJ. Hollenhorst PC, et al. Among authors: mcintosh lp. Annu Rev Biochem. 2011;80:437-71. doi: 10.1146/annurev.biochem.79.081507.103945. Annu Rev Biochem. 2011. PMID: 21548782 Free PMC article. Review.

2

Conformational Dynamics and the Binding of Specific and Nonspecific DNA by the Autoinhibited Transcription Factor Ets-1.

Desjardins G, Okon M, Graves BJ, McIntosh LP. Desjardins G, et al. Among authors: mcintosh lp. Biochemistry. 2016 Jul 26;55(29):4105-18. doi: 10.1021/acs.biochem.6b00460. Epub 2016 Jul 15. Biochemistry. 2016. PMID: 27362745 Free PMC article.

3

Inhibitory module of Ets-1 allosterically regulates DNA binding through a dipole-facilitated phosphate contact.

Wang H, McIntosh LP, Graves BJ. Wang H, et al. Among authors: mcintosh lp. J Biol Chem. 2002 Jan 18;277(3):2225-33. doi: 10.1074/jbc.M109430200. Epub 2001 Oct 31. J Biol Chem. 2002. PMID: 11689571 Free article.

4

The structural and dynamic basis of Ets-1 DNA binding autoinhibition.

Lee GM, Donaldson LW, Pufall MA, Kang HS, Pot I, Graves BJ, McIntosh LP. Lee GM, et al. Among authors: mcintosh lp. J Biol Chem. 2005 Feb 25;280(8):7088-99. doi: 10.1074/jbc.M410722200. Epub 2004 Dec 9. J Biol Chem. 2005. PMID: 15591056 Free article.

5

Variable control of Ets-1 DNA binding by multiple phosphates in an unstructured region.

Pufall MA, Lee GM, Nelson ML, Kang HS, Velyvis A, Kay LE, McIntosh LP, Graves BJ. Pufall MA, et al. Among authors: mcintosh lp. Science. 2005 Jul 1;309(5731):142-5. doi: 10.1126/science.1111915. Science. 2005. PMID: 15994560

6

Beads-on-a-string, characterization of ETS-1 sumoylated within its flexible N-terminal sequence.

Macauley MS, Errington WJ, Schärpf M, Mackereth CD, Blaszczak AG, Graves BJ, McIntosh LP. Macauley MS, et al. Among authors: mcintosh lp. J Biol Chem. 2006 Feb 17;281(7):4164-72. doi: 10.1074/jbc.M510488200. Epub 2005 Nov 29. J Biol Chem. 2006. PMID: 16319071 Free article.

7

The affinity of Ets-1 for DNA is modulated by phosphorylation through transient interactions of an unstructured region.

Lee GM, Pufall MA, Meeker CA, Kang HS, Graves BJ, McIntosh LP. Lee GM, et al. Among authors: mcintosh lp. J Mol Biol. 2008 Oct 17;382(4):1014-30. doi: 10.1016/j.jmb.2008.07.064. Epub 2008 Jul 29. J Mol Biol. 2008. PMID: 18692067 Free PMC article.

8

DNA binding by the ETS protein TEL (ETV6) is regulated by autoinhibition and self-association.

Green SM, Coyne HJ 3rd, McIntosh LP, Graves BJ. Green SM, et al. Among authors: mcintosh lp. J Biol Chem. 2010 Jun 11;285(24):18496-504. doi: 10.1074/jbc.M109.096958. Epub 2010 Apr 16. J Biol Chem. 2010. PMID: 20400516 Free PMC article.

9

Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to coactivator CBP.

Nelson ML, Kang HS, Lee GM, Blaszczak AG, Lau DK, McIntosh LP, Graves BJ. Nelson ML, et al. Among authors: mcintosh lp. Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10026-31. doi: 10.1073/pnas.0915137107. Epub 2010 May 13. Proc Natl Acad Sci U S A. 2010. PMID: 20534573 Free PMC article.

10

Autoinhibition of ETV6 (TEL) DNA binding: appended helices sterically block the ETS domain.

Coyne HJ 3rd, De S, Okon M, Green SM, Bhachech N, Graves BJ, McIntosh LP. Coyne HJ 3rd, et al. Among authors: mcintosh lp. J Mol Biol. 2012 Aug 3;421(1):67-84. doi: 10.1016/j.jmb.2012.05.010. Epub 2012 May 12. J Mol Biol. 2012. PMID: 22584210 Free PMC article.

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