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CFTR Folding Consortium: methods available for studies of CFTR folding and correction.
Peters KW, Okiyoneda T, Balch WE, Braakman I, Brodsky JL, Guggino WB, Penland CM, Pollard HB, Sorscher EJ, Skach WR, Thomas PJ, Lukacs GL, Frizzell RA. Peters KW, et al. Among authors: braakman i. Methods Mol Biol. 2011;742:335-53. doi: 10.1007/978-1-61779-120-8_20. Methods Mol Biol. 2011. PMID: 21547742 Free PMC article.
Folding of CFTR is predominantly cotranslational.
Kleizen B, van Vlijmen T, de Jonge HR, Braakman I. Kleizen B, et al. Among authors: braakman i. Mol Cell. 2005 Oct 28;20(2):277-87. doi: 10.1016/j.molcel.2005.09.007. Mol Cell. 2005. PMID: 16246729 Free article.
Slowing ribosome velocity restores folding and function of mutant CFTR.
Oliver KE, Rauscher R, Mijnders M, Wang W, Wolpert MJ, Maya J, Sabusap CM, Kesterson RA, Kirk KL, Rab A, Braakman I, Hong JS, Hartman JL 4th, Ignatova Z, Sorscher EJ. Oliver KE, et al. Among authors: braakman i. J Clin Invest. 2019 Dec 2;129(12):5236-5253. doi: 10.1172/JCI124282. J Clin Invest. 2019. PMID: 31657788 Free PMC article.
Co-Translational Folding of the First Transmembrane Domain of ABC-Transporter CFTR is Supported by Assembly with the First Cytosolic Domain.
Kleizen B, van Willigen M, Mijnders M, Peters F, Grudniewska M, Hillenaar T, Thomas A, Kooijman L, Peters KW, Frizzell R, van der Sluijs P, Braakman I. Kleizen B, et al. Among authors: braakman i. J Mol Biol. 2021 Jun 25;433(13):166955. doi: 10.1016/j.jmb.2021.166955. Epub 2021 Mar 24. J Mol Biol. 2021. PMID: 33771570 Free article.
The Folding Pathway of ABC Transporter CFTR: Effective and Robust.
van der Sluijs P, Hoelen H, Schmidt A, Braakman I. van der Sluijs P, et al. Among authors: braakman i. J Mol Biol. 2024 Jul 15;436(14):168591. doi: 10.1016/j.jmb.2024.168591. Epub 2024 Apr 26. J Mol Biol. 2024. PMID: 38677493 Free article. Review.
101 results