Chen H - Search Results

1

Synthesis and activity of thioether-containing analogues of the complement inhibitor compstatin.

Knerr PJ, Tzekou A, Ricklin D, Qu H, Chen H, van der Donk WA, Lambris JD. Knerr PJ, et al. Among authors: chen h. ACS Chem Biol. 2011 Jul 15;6(7):753-60. doi: 10.1021/cb2000378. Epub 2011 May 23. ACS Chem Biol. 2011. PMID: 21520911 Free PMC article.

2

New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties.

Qu H, Ricklin D, Bai H, Chen H, Reis ES, Maciejewski M, Tzekou A, DeAngelis RA, Resuello RR, Lupu F, Barlow PN, Lambris JD. Qu H, et al. Among authors: chen h. Immunobiology. 2013 Apr;218(4):496-505. doi: 10.1016/j.imbio.2012.06.003. Epub 2012 Jun 17. Immunobiology. 2013. PMID: 22795972 Free PMC article.

3

Therapeutic C3 inhibitor Cp40 abrogates complement activation induced by modern hemodialysis filters.

Reis ES, DeAngelis RA, Chen H, Resuello RR, Ricklin D, Lambris JD. Reis ES, et al. Among authors: chen h. Immunobiology. 2015 Apr;220(4):476-82. doi: 10.1016/j.imbio.2014.10.026. Epub 2014 Nov 3. Immunobiology. 2015. PMID: 25468722 Free PMC article.

4

Rare loss-of-function mutation in complement component C3 provides insight into molecular and pathophysiological determinants of complement activity.

Sfyroera G, Ricklin D, Reis ES, Chen H, Wu EL, Kaznessis YN, Ekdahl KN, Nilsson B, Lambris JD. Sfyroera G, et al. Among authors: chen h. J Immunol. 2015 Apr 1;194(7):3305-16. doi: 10.4049/jimmunol.1402781. Epub 2015 Feb 23. J Immunol. 2015. PMID: 25712219 Free PMC article.

5

Dynamic structural changes during complement C3 activation analyzed by hydrogen/deuterium exchange mass spectrometry.

Schuster MC, Ricklin D, Papp K, Molnar KS, Coales SJ, Hamuro Y, Sfyroera G, Chen H, Winters MS, Lambris JD. Schuster MC, et al. Among authors: chen h. Mol Immunol. 2008 Jun;45(11):3142-51. doi: 10.1016/j.molimm.2008.03.010. Epub 2008 May 5. Mol Immunol. 2008. PMID: 18456336 Free PMC article.

6

Allosteric inhibition of complement function by a staphylococcal immune evasion protein.

Chen H, Ricklin D, Hammel M, Garcia BL, McWhorter WJ, Sfyroera G, Wu YQ, Tzekou A, Li S, Geisbrecht BV, Woods VL Jr, Lambris JD. Chen H, et al. Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17621-6. doi: 10.1073/pnas.1003750107. Epub 2010 Sep 27. Proc Natl Acad Sci U S A. 2010. PMID: 20876141 Free PMC article.

7

C5a receptor-dependent cell activation by physiological concentrations of desarginated C5a: insights from a novel label-free cellular assay.

Reis ES, Chen H, Sfyroera G, Monk PN, Köhl J, Ricklin D, Lambris JD. Reis ES, et al. Among authors: chen h. J Immunol. 2012 Nov 15;189(10):4797-805. doi: 10.4049/jimmunol.1200834. Epub 2012 Oct 5. J Immunol. 2012. PMID: 23041570 Free PMC article.

8

Induction of complement C3a receptor responses by kallikrein-related peptidase 14.

Oikonomopoulou K, DeAngelis RA, Chen H, Diamandis EP, Hollenberg MD, Ricklin D, Lambris JD. Oikonomopoulou K, et al. Among authors: chen h. J Immunol. 2013 Oct 1;191(7):3858-66. doi: 10.4049/jimmunol.1202999. Epub 2013 Sep 6. J Immunol. 2013. PMID: 24014879 Free PMC article.

9

Peptide inhibitors of C3 activation as a novel strategy of complement inhibition for the treatment of paroxysmal nocturnal hemoglobinuria.

Risitano AM, Ricklin D, Huang Y, Reis ES, Chen H, Ricci P, Lin Z, Pascariello C, Raia M, Sica M, Del Vecchio L, Pane F, Lupu F, Notaro R, Resuello RR, DeAngelis RA, Lambris JD. Risitano AM, et al. Among authors: chen h. Blood. 2014 Mar 27;123(13):2094-101. doi: 10.1182/blood-2013-11-536573. Epub 2014 Feb 4. Blood. 2014. PMID: 24497537 Free PMC article.

10

Hydrogen/deuterium exchange mass spectrometry: potential for investigating innate immunity proteins.

Schuster MC, Chen H, Lambris JD. Schuster MC, et al. Among authors: chen h. Adv Exp Med Biol. 2007;598:407-17. doi: 10.1007/978-0-387-71767-8_28. Adv Exp Med Biol. 2007. PMID: 17892227 Review. No abstract available.

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