Lazar AC - Search Results

1

Synthesis and evaluation of hydrophilic linkers for antibody-maytansinoid conjugates.

Zhao RY, Wilhelm SD, Audette C, Jones G, Leece BA, Lazar AC, Goldmacher VS, Singh R, Kovtun Y, Widdison WC, Lambert JM, Chari RV. Zhao RY, et al. Among authors: lazar ac. J Med Chem. 2011 May 26;54(10):3606-23. doi: 10.1021/jm2002958. Epub 2011 May 4. J Med Chem. 2011. PMID: 21517041

2

Analysis of the composition of immunoconjugates using size-exclusion chromatography coupled to mass spectrometry.

Lazar AC, Wang L, Blättler WA, Amphlett G, Lambert JM, Zhang W. Lazar AC, et al. Rapid Commun Mass Spectrom. 2005;19(13):1806-14. doi: 10.1002/rcm.1987. Rapid Commun Mass Spectrom. 2005. PMID: 15945030

3

Statistics of the distribution of the abundance of molecules with various drug loads in maytansinoid antibody-drug conjugates.

Goldmacher VS, Amphlett G, Wang L, Lazar AC. Goldmacher VS, et al. Among authors: lazar ac. Mol Pharm. 2015 Jun 1;12(6):1738-44. doi: 10.1021/mp5007536. Epub 2015 Feb 17. Mol Pharm. 2015. PMID: 25635630

4

The impact of trisulfide modification of antibodies on the properties of antibody-drug conjugates manufactured using thiol chemistry.

Liu R, Chen X, Dushime J, Bogalhas M, Lazar AC, Ryll T, Wang L. Liu R, et al. Among authors: lazar ac. MAbs. 2017 Apr;9(3):490-497. doi: 10.1080/19420862.2017.1285478. Epub 2017 Jan 31. MAbs. 2017. PMID: 28136017 Free PMC article.

5

Determination of charge heterogeneity and level of unconjugated antibody by imaged cIEF.

Lin J, Lazar AC. Lin J, et al. Among authors: lazar ac. Methods Mol Biol. 2013;1045:295-302. doi: 10.1007/978-1-62703-541-5_19. Methods Mol Biol. 2013. PMID: 23913156

6

An Industry Perspective on Forced Degradation Studies of Biopharmaceuticals: Survey Outcome and Recommendations.

Halley J, Chou YR, Cicchino C, Huang M, Sharma V, Tan NC, Thakkar S, Zhou LL, Al-Azzam W, Cornen S, Gauden M, Gu Z, Kar S, Lazar AC, Mehndiratta P, Smith J, Sosic Z, Weisbach P, Stokes ESE. Halley J, et al. Among authors: lazar ac. J Pharm Sci. 2020 Jan;109(1):6-21. doi: 10.1016/j.xphs.2019.09.018. Epub 2019 Sep 26. J Pharm Sci. 2020. PMID: 31563512

7

Identification and characterization of co-purifying CHO host cell proteins in monoclonal antibody purification process.

Liu X, Chen Y, Zhao Y, Liu-Compton V, Chen W, Payne G, Lazar AC. Liu X, et al. Among authors: lazar ac. J Pharm Biomed Anal. 2019 Sep 10;174:500-508. doi: 10.1016/j.jpba.2019.06.021. Epub 2019 Jun 18. J Pharm Biomed Anal. 2019. PMID: 31234041

8

Methods comparison of two-dimensional gel electrophoresis for host cell protein characterization.

King A, Zhao Y, Lazar A, Capron M, Thiruvur N, Liu X. King A, et al. Biotechnol Prog. 2024 Jul-Aug;40(4):e3452. doi: 10.1002/btpr.3452. Epub 2024 Mar 18. Biotechnol Prog. 2024. PMID: 38494896

9

Clinical, histopathological and immunohistochemical changes of the superficial marginal periodontium caused by orthodontic treatment with fixed metallic orthodontic appliances.

Katta M, Cumpătă CN, Ţuculină MJ, Lazăr AC, Manolea HO, Mocanu H, Mărăşescu FI, Petrescu SMS, Dascălu IT. Katta M, et al. Among authors: lazar ac. Rom J Morphol Embryol. 2022 Apr-Jun;63(2):431-438. doi: 10.47162/RJME.63.2.14. Rom J Morphol Embryol. 2022. PMID: 36374148 Free PMC article.

10

Legal approach regarding dental malpractice in Romania.

Lazăr AC, Buhăţel D, Mureşan O, Todor L, Păcurar M. Lazăr AC, et al. Rom J Morphol Embryol. 2021 Jan-Mar;62(1):319-323. doi: 10.47162/RJME.62.1.36. Rom J Morphol Embryol. 2021. PMID: 34609439 Free PMC article.

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