López-Izquierdo A - Search Results

1

The antimalarial drug mefloquine inhibits cardiac inward rectifier K+ channels: evidence for interference in PIP2-channel interaction.

López-Izquierdo A, Ponce-Balbuena D, Moreno-Galindo EG, Aréchiga-Figueroa IA, Rodríguez-Martínez M, Ferrer T, Rodríguez-Menchaca AA, Sánchez-Chapula JA. López-Izquierdo A, et al. J Cardiovasc Pharmacol. 2011 Apr;57(4):407-15. doi: 10.1097/FJC.0b013e31820b7c03. J Cardiovasc Pharmacol. 2011. PMID: 21502926

2

Tamoxifen inhibits inward rectifier K+ 2.x family of inward rectifier channels by interfering with phosphatidylinositol 4,5-bisphosphate-channel interactions.

Ponce-Balbuena D, López-Izquierdo A, Ferrer T, Rodríguez-Menchaca AA, Aréchiga-Figueroa IA, Sánchez-Chapula JA. Ponce-Balbuena D, et al. J Pharmacol Exp Ther. 2009 Nov;331(2):563-73. doi: 10.1124/jpet.109.156075. Epub 2009 Aug 4. J Pharmacol Exp Ther. 2009. PMID: 19654266

3

Chloroquine blocks a mutant Kir2.1 channel responsible for short QT syndrome and normalizes repolarization properties in silico.

Lopez-Izquierdo A, Ponce-Balbuena D, Ferrer T, Sachse FB, Tristani-Firouzi M, Sanchez-Chapula JA. Lopez-Izquierdo A, et al. Cell Physiol Biochem. 2009;24(3-4):153-60. doi: 10.1159/000233241. Epub 2009 Aug 3. Cell Physiol Biochem. 2009. PMID: 19710529 Free PMC article.

4

Thiopental inhibits function of different inward rectifying potassium channel isoforms by a similar mechanism.

López-Izquierdo A, Ponce-Balbuena D, Ferrer T, Rodríguez-Menchaca AA, Sánchez-Chapula JA. López-Izquierdo A, et al. Eur J Pharmacol. 2010 Jul 25;638(1-3):33-41. doi: 10.1016/j.ejphar.2010.04.026. Epub 2010 May 4. Eur J Pharmacol. 2010. PMID: 20447386

5

Tamoxifen inhibits cardiac ATP-sensitive and acetylcholine-activated K+ currents in part by interfering with phosphatidylinositol 4,5-bisphosphate-channel interaction.

Ponce-Balbuena D, Moreno-Galindo EG, López-Izquierdo A, Ferrer T, Sánchez-Chapula JA. Ponce-Balbuena D, et al. J Pharmacol Sci. 2010;113(1):66-75. doi: 10.1254/jphs.10024fp. J Pharmacol Sci. 2010. PMID: 20472984 Free article.

6

Carvedilol inhibits Kir2.3 channels by interference with PIP₂-channel interaction.

Ferrer T, Ponce-Balbuena D, López-Izquierdo A, Aréchiga-Figueroa IA, de Boer TP, van der Heyden MA, Sánchez-Chapula JA. Ferrer T, et al. Eur J Pharmacol. 2011 Oct 1;668(1-2):72-7. doi: 10.1016/j.ejphar.2011.05.067. Epub 2011 Jun 6. Eur J Pharmacol. 2011. PMID: 21663737

7

Mechanisms for Kir channel inhibition by quinacrine: acute pore block of Kir2.x channels and interference in PIP2 interaction with Kir2.x and Kir6.2 channels.

López-Izquierdo A, Aréchiga-Figueroa IA, Moreno-Galindo EG, Ponce-Balbuena D, Rodríguez-Martínez M, Ferrer-Villada T, Rodríguez-Menchaca AA, van der Heyden MA, Sánchez-Chapula JA. López-Izquierdo A, et al. Pflugers Arch. 2011 Oct;462(4):505-17. doi: 10.1007/s00424-011-0995-5. Epub 2011 Jul 22. Pflugers Arch. 2011. PMID: 21779761

8

Molecular mechanisms of chloroquine inhibition of heterologously expressed Kir6.2/SUR2A channels.

Ponce-Balbuena D, Rodríguez-Menchaca AA, López-Izquierdo A, Ferrer T, Kurata HT, Nichols CG, Sánchez-Chapula JA. Ponce-Balbuena D, et al. Among authors: lopez izquierdo a. Mol Pharmacol. 2012 Nov;82(5):803-13. doi: 10.1124/mol.112.079152. Epub 2012 Jul 31. Mol Pharmacol. 2012. PMID: 22851715 Free PMC article.

9

Structural bases for the different anti-fibrillatory effects of chloroquine and quinidine.

Noujaim SF, Stuckey JA, Ponce-Balbuena D, Ferrer-Villada T, López-Izquierdo A, Pandit SV, Sánchez-Chapula JA, Jalife J. Noujaim SF, et al. Cardiovasc Res. 2011 Mar 1;89(4):862-9. doi: 10.1093/cvr/cvr008. Epub 2011 Jan 13. Cardiovasc Res. 2011. PMID: 21233253 Free PMC article.

10

ABCC9 is a novel Brugada and early repolarization syndrome susceptibility gene.

Hu D, Barajas-Martínez H, Terzic A, Park S, Pfeiffer R, Burashnikov E, Wu Y, Borggrefe M, Veltmann C, Schimpf R, Cai JJ, Nam GB, Deshmukh P, Scheinman M, Preminger M, Steinberg J, López-Izquierdo A, Ponce-Balbuena D, Wolpert C, Haïssaguerre M, Sánchez-Chapula JA, Antzelevitch C. Hu D, et al. Among authors: lopez izquierdo a. Int J Cardiol. 2014 Feb 15;171(3):431-42. doi: 10.1016/j.ijcard.2013.12.084. Epub 2014 Jan 4. Int J Cardiol. 2014. PMID: 24439875 Free PMC article.

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