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A new pharmacological agent (AKB-4924) stabilizes hypoxia inducible factor-1 (HIF-1) and increases skin innate defenses against bacterial infection.
Okumura CY, Hollands A, Tran DN, Olson J, Dahesh S, von Köckritz-Blickwede M, Thienphrapa W, Corle C, Jeung SN, Kotsakis A, Shalwitz RA, Johnson RS, Nizet V. Okumura CY, et al. J Mol Med (Berl). 2012 Sep;90(9):1079-89. doi: 10.1007/s00109-012-0882-3. Epub 2012 Feb 28. J Mol Med (Berl). 2012. PMID: 22371073 Free PMC article.
Statins enhance formation of phagocyte extracellular traps.
Chow OA, von Köckritz-Blickwede M, Bright AT, Hensler ME, Zinkernagel AS, Cogen AL, Gallo RL, Monestier M, Wang Y, Glass CK, Nizet V. Chow OA, et al. Cell Host Microbe. 2010 Nov 18;8(5):445-54. doi: 10.1016/j.chom.2010.10.005. Cell Host Microbe. 2010. PMID: 21075355 Free PMC article.
140 results