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Comparative metabolism of 1,2,3,3,3-pentafluoropropene in male and female mouse, rat, dog, and human liver microsomes and cytosol and male rat hepatocytes via oxidative dehalogenation and glutathione S-conjugation pathways.
Han X, Szostek B, Yang CH, Cheatham SF, Mingoia RT, Nabb DL, Gannon SA, Himmelstein MW, Jepson GW. Han X, et al. Among authors: mingoia rt. Drug Metab Dispos. 2011 Jul;39(7):1288-93. doi: 10.1124/dmd.111.038299. Epub 2011 Apr 14. Drug Metab Dispos. 2011. PMID: 21493824
Xenobiotic intrinsic clearance in freshly isolated hepatocytes from rainbow trout (Oncorhynchus mykiss): determination of trout hepatocellularity, optimization of cell concentrations and comparison of serum and serum-free incubations.
Han X, Mingoia RT, Nabb DL, Yang CH, Snajdr SI, Hoke RA. Han X, et al. Among authors: mingoia rt. Aquat Toxicol. 2008 Aug 11;89(1):11-7. doi: 10.1016/j.aquatox.2008.05.010. Epub 2008 May 23. Aquat Toxicol. 2008. PMID: 18599132
Non-coplanar 2,2',3,3',4,4',5,5',6,6'-decachlorobiphenyl (PCB 209) did not induce cytochrome P450 enzyme activities in primary cultured rat hepatocytes, was not genotoxic, and did not exhibit endocrine-modulating activities.
Han X, O'Connor JC, Donner EM, Nabb DL, Mingoia RT, Snajdr SI, Clarke JJ, Kaplan AM. Han X, et al. Among authors: mingoia rt. Toxicology. 2009 Jan 31;255(3):177-86. doi: 10.1016/j.tox.2008.10.013. Epub 2008 Oct 31. Toxicology. 2009. PMID: 19022331
17 results