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Page 1
Sucrose induces fatty liver and pancreatic inflammation in male breeder rats independent of excess energy intake.
Roncal-Jimenez CA, Lanaspa MA, Rivard CJ, Nakagawa T, Sanchez-Lozada LG, Jalal D, Andres-Hernando A, Tanabe K, Madero M, Li N, Cicerchi C, Mc Fann K, Sautin YY, Johnson RJ. Roncal-Jimenez CA, et al. Among authors: sautin yy. Metabolism. 2011 Sep;60(9):1259-70. doi: 10.1016/j.metabol.2011.01.008. Epub 2011 Apr 12. Metabolism. 2011. PMID: 21489572 Free PMC article.
Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice.
Ishimoto T, Lanaspa MA, Le MT, Garcia GE, Diggle CP, Maclean PS, Jackman MR, Asipu A, Roncal-Jimenez CA, Kosugi T, Rivard CJ, Maruyama S, Rodriguez-Iturbe B, Sánchez-Lozada LG, Bonthron DT, Sautin YY, Johnson RJ. Ishimoto T, et al. Among authors: sautin yy. Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4320-5. doi: 10.1073/pnas.1119908109. Epub 2012 Feb 27. Proc Natl Acad Sci U S A. 2012. PMID: 22371574 Free PMC article.
Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: potential role in fructose-dependent and -independent fatty liver.
Lanaspa MA, Sanchez-Lozada LG, Choi YJ, Cicerchi C, Kanbay M, Roncal-Jimenez CA, Ishimoto T, Li N, Marek G, Duranay M, Schreiner G, Rodriguez-Iturbe B, Nakagawa T, Kang DH, Sautin YY, Johnson RJ. Lanaspa MA, et al. Among authors: sautin yy. J Biol Chem. 2012 Nov 23;287(48):40732-44. doi: 10.1074/jbc.M112.399899. Epub 2012 Oct 3. J Biol Chem. 2012. PMID: 23035112 Free PMC article.
Uric acid stimulates fructokinase and accelerates fructose metabolism in the development of fatty liver.
Lanaspa MA, Sanchez-Lozada LG, Cicerchi C, Li N, Roncal-Jimenez CA, Ishimoto T, Le M, Garcia GE, Thomas JB, Rivard CJ, Andres-Hernando A, Hunter B, Schreiner G, Rodriguez-Iturbe B, Sautin YY, Johnson RJ. Lanaspa MA, et al. Among authors: sautin yy. PLoS One. 2012;7(10):e47948. doi: 10.1371/journal.pone.0047948. Epub 2012 Oct 24. PLoS One. 2012. PMID: 23112875 Free PMC article.
High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase.
Ishimoto T, Lanaspa MA, Rivard CJ, Roncal-Jimenez CA, Orlicky DJ, Cicerchi C, McMahan RH, Abdelmalek MF, Rosen HR, Jackman MR, MacLean PS, Diggle CP, Asipu A, Inaba S, Kosugi T, Sato W, Maruyama S, Sánchez-Lozada LG, Sautin YY, Hill JO, Bonthron DT, Johnson RJ. Ishimoto T, et al. Among authors: sautin yy. Hepatology. 2013 Nov;58(5):1632-43. doi: 10.1002/hep.26594. Epub 2013 Oct 8. Hepatology. 2013. PMID: 23813872 Free PMC article.
Sugar, uric acid, and the etiology of diabetes and obesity.
Johnson RJ, Nakagawa T, Sanchez-Lozada LG, Shafiu M, Sundaram S, Le M, Ishimoto T, Sautin YY, Lanaspa MA. Johnson RJ, et al. Among authors: sautin yy. Diabetes. 2013 Oct;62(10):3307-15. doi: 10.2337/db12-1814. Diabetes. 2013. PMID: 24065788 Free PMC article. Review.
Uric acid and fructose: potential biological mechanisms.
Lanaspa MA, Tapia E, Soto V, Sautin Y, Sánchez-Lozada LG. Lanaspa MA, et al. Semin Nephrol. 2011 Sep;31(5):426-32. doi: 10.1016/j.semnephrol.2011.08.006. Semin Nephrol. 2011. PMID: 22000649 Review.
Hypothesis: could excessive fructose intake and uric acid cause type 2 diabetes?
Johnson RJ, Perez-Pozo SE, Sautin YY, Manitius J, Sanchez-Lozada LG, Feig DI, Shafiu M, Segal M, Glassock RJ, Shimada M, Roncal C, Nakagawa T. Johnson RJ, et al. Among authors: sautin yy. Endocr Rev. 2009 Feb;30(1):96-116. doi: 10.1210/er.2008-0033. Epub 2009 Jan 16. Endocr Rev. 2009. PMID: 19151107 Free PMC article. Review.
45 results