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Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis.
Alvarez H, Opalinska J, Zhou L, Sohal D, Fazzari MJ, Yu Y, Montagna C, Montgomery EA, Canto M, Dunbar KB, Wang J, Roa JC, Mo Y, Bhagat T, Ramesh KH, Cannizzaro L, Mollenhauer J, Thompson RF, Suzuki M, Meltzer SJ, Melnick A, Greally JM, Maitra A, Verma A. Alvarez H, et al. Among authors: wang j. PLoS Genet. 2011 Mar;7(3):e1001356. doi: 10.1371/journal.pgen.1001356. Epub 2011 Mar 31. PLoS Genet. 2011. PMID: 21483804 Free PMC article.
Three-tiered risk stratification model to predict progression in Barrett's esophagus using epigenetic and clinical features.
Sato F, Jin Z, Schulmann K, Wang J, Greenwald BD, Ito T, Kan T, Hamilton JP, Yang J, Paun B, David S, Olaru A, Cheng Y, Mori Y, Abraham JM, Yfantis HG, Wu TT, Fredericksen MB, Wang KK, Canto M, Romero Y, Feng Z, Meltzer SJ. Sato F, et al. Among authors: wang kk, wang j. PLoS One. 2008 Apr 2;3(4):e1890. doi: 10.1371/journal.pone.0001890. PLoS One. 2008. PMID: 18382671 Free PMC article.
Mesothelin is a specific biomarker of invasive cancer in the Barrett-associated adenocarcinoma progression model: translational implications for diagnosis and therapy.
Alvarez H, Rojas PL, Yong KT, Ding H, Xu G, Prasad PN, Wang J, Canto M, Eshleman JR, Montgomery EA, Maitra A. Alvarez H, et al. Among authors: wang j. Nanomedicine. 2008 Dec;4(4):295-301. doi: 10.1016/j.nano.2008.06.006. Epub 2008 Aug 8. Nanomedicine. 2008. PMID: 18691948 Free PMC article.
A multicenter, double-blinded validation study of methylation biomarkers for progression prediction in Barrett's esophagus.
Jin Z, Cheng Y, Gu W, Zheng Y, Sato F, Mori Y, Olaru AV, Paun BC, Yang J, Kan T, Ito T, Hamilton JP, Selaru FM, Agarwal R, David S, Abraham JM, Wolfsen HC, Wallace MB, Shaheen NJ, Washington K, Wang J, Canto MI, Bhattacharyya A, Nelson MA, Wagner PD, Romero Y, Wang KK, Feng Z, Sampliner RE, Meltzer SJ. Jin Z, et al. Among authors: wang kk, wang j. Cancer Res. 2009 May 15;69(10):4112-5. doi: 10.1158/0008-5472.CAN-09-0028. Epub 2009 May 12. Cancer Res. 2009. PMID: 19435894 Free PMC article.
Aberrant epithelial-mesenchymal Hedgehog signaling characterizes Barrett's metaplasia.
Wang DH, Clemons NJ, Miyashita T, Dupuy AJ, Zhang W, Szczepny A, Corcoran-Schwartz IM, Wilburn DL, Montgomery EA, Wang JS, Jenkins NA, Copeland NA, Harmon JW, Phillips WA, Watkins DN. Wang DH, et al. Among authors: wang js. Gastroenterology. 2010 May;138(5):1810-22. doi: 10.1053/j.gastro.2010.01.048. Epub 2010 Feb 4. Gastroenterology. 2010. PMID: 20138038 Free PMC article.
The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma.
Hector A, Montgomery EA, Karikari C, Canto M, Dunbar KB, Wang JS, Feldmann G, Hong SM, Haffner MC, Meeker AK, Holland SJ, Yu J, Heckrodt TJ, Zhang J, Ding P, Goff D, Singh R, Roa JC, Marimuthu A, Riggins GJ, Eshleman JR, Nelkin BD, Pandey A, Maitra A. Hector A, et al. Among authors: wang js. Cancer Biol Ther. 2010 Nov 15;10(10):1009-18. doi: 10.4161/cbt.10.10.13248. Epub 2010 Nov 15. Cancer Biol Ther. 2010. PMID: 20818175 Free PMC article.
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