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Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis.
Alvarez H, Opalinska J, Zhou L, Sohal D, Fazzari MJ, Yu Y, Montagna C, Montgomery EA, Canto M, Dunbar KB, Wang J, Roa JC, Mo Y, Bhagat T, Ramesh KH, Cannizzaro L, Mollenhauer J, Thompson RF, Suzuki M, Meltzer SJ, Melnick A, Greally JM, Maitra A, Verma A. Alvarez H, et al. PLoS Genet. 2011 Mar;7(3):e1001356. doi: 10.1371/journal.pgen.1001356. Epub 2011 Mar 31. PLoS Genet. 2011. PMID: 21483804 Free PMC article.
An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer.
Feldmann G, Fendrich V, McGovern K, Bedja D, Bisht S, Alvarez H, Koorstra JB, Habbe N, Karikari C, Mullendore M, Gabrielson KL, Sharma R, Matsui W, Maitra A. Feldmann G, et al. Among authors: alvarez h. Mol Cancer Ther. 2008 Sep;7(9):2725-35. doi: 10.1158/1535-7163.MCT-08-0573. Mol Cancer Ther. 2008. PMID: 18790753 Free PMC article.
Application of a global proteomic approach to archival precursor lesions: deleted in malignant brain tumors 1 and tissue transglutaminase 2 are upregulated in pancreatic cancer precursors.
Cheung W, Darfler MM, Alvarez H, Hood BL, Conrads TP, Habbe N, Krizman DB, Mollenhauer J, Feldmann G, Maitra A. Cheung W, et al. Among authors: alvarez h. Pancreatology. 2008;8(6):608-16. doi: 10.1159/000161012. Epub 2008 Oct 13. Pancreatology. 2008. PMID: 18849643 Free PMC article.
430 results