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Fluid shear stress induces upregulation of COX-2 and PGI2 release in endothelial cells via a pathway involving PECAM-1, PI3K, FAK, and p38.
Russell-Puleri S, Dela Paz NG, Adams D, Chattopadhyay M, Cancel L, Ebong E, Orr AW, Frangos JA, Tarbell JM. Russell-Puleri S, et al. Am J Physiol Heart Circ Physiol. 2017 Mar 1;312(3):H485-H500. doi: 10.1152/ajpheart.00035.2016. Epub 2016 Dec 23. Am J Physiol Heart Circ Physiol. 2017. PMID: 28011582 Free PMC article.
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