de Laat W - Search Results

1

Diverse gene reprogramming events occur in the same spatial clusters of distal regulatory elements.

Hakim O, Sung MH, Voss TC, Splinter E, John S, Sabo PJ, Thurman RE, Stamatoyannopoulos JA, de Laat W, Hager GL. Hakim O, et al. Among authors: de laat w. Genome Res. 2011 May;21(5):697-706. doi: 10.1101/gr.111153.110. Epub 2011 Apr 6. Genome Res. 2011. PMID: 21471403 Free PMC article.

2

Looping and interaction between hypersensitive sites in the active beta-globin locus.

Tolhuis B, Palstra RJ, Splinter E, Grosveld F, de Laat W. Tolhuis B, et al. Among authors: de laat w. Mol Cell. 2002 Dec;10(6):1453-65. doi: 10.1016/s1097-2765(02)00781-5. Mol Cell. 2002. PMID: 12504019 Free article.

3

The beta-globin nuclear compartment in development and erythroid differentiation.

Palstra RJ, Tolhuis B, Splinter E, Nijmeijer R, Grosveld F, de Laat W. Palstra RJ, et al. Among authors: de laat w. Nat Genet. 2003 Oct;35(2):190-4. doi: 10.1038/ng1244. Epub 2003 Sep 21. Nat Genet. 2003. PMID: 14517543

4

3C technology: analyzing the spatial organization of genomic loci in vivo.

Splinter E, Grosveld F, de Laat W. Splinter E, et al. Among authors: de laat w. Methods Enzymol. 2004;375:493-507. doi: 10.1016/s0076-6879(03)75030-7. Methods Enzymol. 2004. PMID: 14870685 No abstract available.

5

The active spatial organization of the beta-globin locus requires the transcription factor EKLF.

Drissen R, Palstra RJ, Gillemans N, Splinter E, Grosveld F, Philipsen S, de Laat W. Drissen R, et al. Among authors: de laat w. Genes Dev. 2004 Oct 15;18(20):2485-90. doi: 10.1101/gad.317004. Genes Dev. 2004. PMID: 15489291 Free PMC article.

6

CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus.

Splinter E, Heath H, Kooren J, Palstra RJ, Klous P, Grosveld F, Galjart N, de Laat W. Splinter E, et al. Among authors: de laat w. Genes Dev. 2006 Sep 1;20(17):2349-54. doi: 10.1101/gad.399506. Genes Dev. 2006. PMID: 16951251 Free PMC article.

7

Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C).

Simonis M, Klous P, Splinter E, Moshkin Y, Willemsen R, de Wit E, van Steensel B, de Laat W. Simonis M, et al. Among authors: de laat w, de wit e. Nat Genet. 2006 Nov;38(11):1348-54. doi: 10.1038/ng1896. Epub 2006 Oct 8. Nat Genet. 2006. PMID: 17033623

8

Beta-globin active chromatin Hub formation in differentiating erythroid cells and in p45 NF-E2 knock-out mice.

Kooren J, Palstra RJ, Klous P, Splinter E, von Lindern M, Grosveld F, de Laat W. Kooren J, et al. Among authors: de laat w. J Biol Chem. 2007 Jun 1;282(22):16544-52. doi: 10.1074/jbc.M701159200. Epub 2007 Apr 11. J Biol Chem. 2007. PMID: 17428799 Free article.

9

Quantitative analysis of chromosome conformation capture assays (3C-qPCR).

Hagège H, Klous P, Braem C, Splinter E, Dekker J, Cathala G, de Laat W, Forné T. Hagège H, et al. Among authors: de laat w. Nat Protoc. 2007;2(7):1722-33. doi: 10.1038/nprot.2007.243. Nat Protoc. 2007. PMID: 17641637

10

Three-dimensional organization of gene expression in erythroid cells.

de Laat W, Klous P, Kooren J, Noordermeer D, Palstra RJ, Simonis M, Splinter E, Grosveld F. de Laat W, et al. Curr Top Dev Biol. 2008;82:117-39. doi: 10.1016/S0070-2153(07)00005-1. Curr Top Dev Biol. 2008. PMID: 18282519 Review.

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