Cavanaugh A - Search Results

1

Behind the curtain: cellular mechanisms for allosteric modulation of calcium-sensing receptors.

Cavanaugh A, Huang Y, Breitwieser GE. Cavanaugh A, et al. Br J Pharmacol. 2012 Mar;165(6):1670-1677. doi: 10.1111/j.1476-5381.2011.01403.x. Br J Pharmacol. 2012. PMID: 21470201 Free PMC article. Review.

2

Pharmacochaperone-mediated rescue of calcium-sensing receptor loss-of-function mutants.

White E, McKenna J, Cavanaugh A, Breitwieser GE. White E, et al. Among authors: cavanaugh a. Mol Endocrinol. 2009 Jul;23(7):1115-23. doi: 10.1210/me.2009-0041. Epub 2009 Apr 23. Mol Endocrinol. 2009. PMID: 19389809 Free PMC article.

3

Calcium-sensing receptor biosynthesis includes a cotranslational conformational checkpoint and endoplasmic reticulum retention.

Cavanaugh A, McKenna J, Stepanchick A, Breitwieser GE. Cavanaugh A, et al. J Biol Chem. 2010 Jun 25;285(26):19854-64. doi: 10.1074/jbc.M110.124792. Epub 2010 Apr 26. J Biol Chem. 2010. PMID: 20421307 Free PMC article.

4

Regulation of stability and trafficking of calcium-sensing receptors by pharmacologic chaperones.

Huang Y, Cavanaugh A, Breitwieser GE. Huang Y, et al. Among authors: cavanaugh a. Adv Pharmacol. 2011;62:143-73. doi: 10.1016/B978-0-12-385952-5.00007-5. Adv Pharmacol. 2011. PMID: 21907909 Review.

5

Agonist-driven maturation and plasma membrane insertion of calcium-sensing receptors dynamically control signal amplitude.

Grant MP, Stepanchick A, Cavanaugh A, Breitwieser GE. Grant MP, et al. Among authors: cavanaugh a. Sci Signal. 2011 Nov 22;4(200):ra78. doi: 10.1126/scisignal.2002208. Sci Signal. 2011. PMID: 22114145

6

14-3-3 Proteins Buffer Intracellular Calcium Sensing Receptors to Constrain Signaling.

Grant MP, Cavanaugh A, Breitwieser GE. Grant MP, et al. Among authors: cavanaugh a. PLoS One. 2015 Aug 28;10(8):e0136702. doi: 10.1371/journal.pone.0136702. eCollection 2015. PLoS One. 2015. PMID: 26317416 Free PMC article.

7

Combined inhibition of heat shock proteins 90 and 70 leads to simultaneous degradation of the oncogenic signaling proteins involved in muscle invasive bladder cancer.

Cavanaugh A, Juengst B, Sheridan K, Danella JF, Williams H. Cavanaugh A, et al. Oncotarget. 2015 Nov 24;6(37):39821-38. doi: 10.18632/oncotarget.5496. Oncotarget. 2015. PMID: 26556859 Free PMC article.

8

DNA binding by the ribosomal DNA transcription factor rrn3 is essential for ribosomal DNA transcription.

Stepanchick A, Zhi H, Cavanaugh AH, Rothblum K, Schneider DA, Rothblum LI. Stepanchick A, et al. Among authors: cavanaugh ah. J Biol Chem. 2013 Mar 29;288(13):9135-44. doi: 10.1074/jbc.M112.444265. Epub 2013 Feb 7. J Biol Chem. 2013. PMID: 23393135 Free PMC article.

9

Rrn3 phosphorylation is a regulatory checkpoint for ribosome biogenesis.

Cavanaugh AH, Hirschler-Laszkiewicz I, Hu Q, Dundr M, Smink T, Misteli T, Rothblum LI. Cavanaugh AH, et al. J Biol Chem. 2002 Jul 26;277(30):27423-32. doi: 10.1074/jbc.M201232200. Epub 2002 May 15. J Biol Chem. 2002. PMID: 12015311 Free article.

10

Rrn3 becomes inactivated in the process of ribosomal DNA transcription.

Hirschler-Laszkiewicz I, Cavanaugh AH, Mirza A, Lun M, Hu Q, Smink T, Rothblum LI. Hirschler-Laszkiewicz I, et al. Among authors: cavanaugh ah. J Biol Chem. 2003 May 23;278(21):18953-9. doi: 10.1074/jbc.M301093200. Epub 2003 Mar 19. J Biol Chem. 2003. PMID: 12646563 Free article.

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