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Page 1
Characterization of genome-wide p53-binding sites upon stress response.
Smeenk L, van Heeringen SJ, Koeppel M, van Driel MA, Bartels SJ, Akkers RC, Denissov S, Stunnenberg HG, Lohrum M. Smeenk L, et al. Nucleic Acids Res. 2008 Jun;36(11):3639-54. doi: 10.1093/nar/gkn232. Epub 2008 May 12. Nucleic Acids Res. 2008. PMID: 18474530 Free PMC article.
Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus.
Kouwenhoven EN, van Heeringen SJ, Tena JJ, Oti M, Dutilh BE, Alonso ME, de la Calle-Mustienes E, Smeenk L, Rinne T, Parsaulian L, Bolat E, Jurgelenaite R, Huynen MA, Hoischen A, Veltman JA, Brunner HG, Roscioli T, Oates E, Wilson M, Manzanares M, Gómez-Skarmeta JL, Stunnenberg HG, Lohrum M, van Bokhoven H, Zhou H. Kouwenhoven EN, et al. Among authors: smeenk l. PLoS Genet. 2010 Aug 19;6(8):e1001065. doi: 10.1371/journal.pgen.1001065. PLoS Genet. 2010. PMID: 20808887 Free PMC article.
Role of p53 serine 46 in p53 target gene regulation.
Smeenk L, van Heeringen SJ, Koeppel M, Gilbert B, Janssen-Megens E, Stunnenberg HG, Lohrum M. Smeenk L, et al. PLoS One. 2011 Mar 4;6(3):e17574. doi: 10.1371/journal.pone.0017574. PLoS One. 2011. PMID: 21394211 Free PMC article.
5-Lipoxygenase is a direct p53 target gene in humans.
Gilbert B, Ahmad K, Roos J, Lehmann C, Chiba T, Ulrich-Rückert S, Smeenk L, van Heeringen S, Maier TJ, Groner B, Steinhilber D. Gilbert B, et al. Among authors: smeenk l. Biochim Biophys Acta. 2015 Aug;1849(8):1003-16. doi: 10.1016/j.bbagrm.2015.06.004. Epub 2015 Jun 9. Biochim Biophys Acta. 2015. PMID: 26070487
Atypical 3q26/MECOM rearrangements genocopy inv(3)/t(3;3) in acute myeloid leukemia.
Ottema S, Mulet-Lazaro R, Beverloo HB, Erpelinck C, van Herk S, van der Helm R, Havermans M, Grob T, Valk PJM, Bindels E, Haferlach T, Haferlach C, Smeenk L, Delwel R. Ottema S, et al. Among authors: smeenk l. Blood. 2020 Jul 9;136(2):224-234. doi: 10.1182/blood.2019003701. Blood. 2020. PMID: 32219447 Free article.
The leukemic oncogene EVI1 hijacks a MYC super-enhancer by CTCF-facilitated loops.
Ottema S, Mulet-Lazaro R, Erpelinck-Verschueren C, van Herk S, Havermans M, Arricibita Varea A, Vermeulen M, Beverloo HB, Gröschel S, Haferlach T, Haferlach C, J Wouters B, Bindels E, Smeenk L, Delwel R. Ottema S, et al. Among authors: smeenk l. Nat Commun. 2021 Sep 28;12(1):5679. doi: 10.1038/s41467-021-25862-3. Nat Commun. 2021. PMID: 34584081 Free PMC article.
30 results