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Discovery of LOU064 (Remibrutinib), a Potent and Highly Selective Covalent Inhibitor of Bruton's Tyrosine Kinase.
Angst D, Gessier F, Janser P, Vulpetti A, Wälchli R, Beerli C, Littlewood-Evans A, Dawson J, Nuesslein-Hildesheim B, Wieczorek G, Gutmann S, Scheufler C, Hinniger A, Zimmerlin A, Funhoff EG, Pulz R, Cenni B. Angst D, et al. Among authors: funhoff eg. J Med Chem. 2020 May 28;63(10):5102-5118. doi: 10.1021/acs.jmedchem.9b01916. Epub 2020 Mar 4. J Med Chem. 2020. PMID: 32083858
Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice.
Lempiäinen H, Müller A, Brasa S, Teo SS, Roloff TC, Morawiec L, Zamurovic N, Vicart A, Funhoff E, Couttet P, Schübeler D, Grenet O, Marlowe J, Moggs J, Terranova R. Lempiäinen H, et al. Among authors: funhoff e. PLoS One. 2011 Mar 24;6(3):e18216. doi: 10.1371/journal.pone.0018216. PLoS One. 2011. PMID: 21455306 Free PMC article.
Alkane hydroxylases involved in microbial alkane degradation.
van Beilen JB, Funhoff EG. van Beilen JB, et al. Among authors: funhoff eg. Appl Microbiol Biotechnol. 2007 Feb;74(1):13-21. doi: 10.1007/s00253-006-0748-0. Epub 2007 Jan 11. Appl Microbiol Biotechnol. 2007. PMID: 17216462 Review.
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