Payza K - Search Results

1

Preclinical pharmacology of AZD2327: a highly selective agonist of the δ-opioid receptor.

Hudzik TJ, Maciag C, Smith MA, Caccese R, Pietras MR, Bui KH, Coupal M, Adam L, Payza K, Griffin A, Smagin G, Song D, Swedberg MD, Brown W. Hudzik TJ, et al. Among authors: payza k. J Pharmacol Exp Ther. 2011 Jul;338(1):195-204. doi: 10.1124/jpet.111.179432. Epub 2011 Mar 28. J Pharmacol Exp Ther. 2011. PMID: 21444630

2

Antiparkinson potential of delta-opioid receptor agonists.

Hudzik TJ, Howell A, Payza K, Cross AJ. Hudzik TJ, et al. Among authors: payza k. Eur J Pharmacol. 2000 May 19;396(2-3):101-7. doi: 10.1016/s0014-2999(00)00209-0. Eur J Pharmacol. 2000. PMID: 10822062

3

Discovery and pharmacological characterization of a small-molecule antagonist at neuromedin U receptor NMUR2.

Liu JJ, Payza K, Huang J, Liu R, Chen T, Coupal M, Laird JM, Cao CQ, Butterworth J, Lapointe S, Bayrakdarian M, Trivedi S, Bostwick JR. Liu JJ, et al. Among authors: payza k. J Pharmacol Exp Ther. 2009 Jul;330(1):268-75. doi: 10.1124/jpet.109.152967. Epub 2009 Apr 15. J Pharmacol Exp Ther. 2009. PMID: 19369576

4

Pharmacologic Profile of Naloxegol, a Peripherally Acting µ-Opioid Receptor Antagonist, for the Treatment of Opioid-Induced Constipation.

Floettmann E, Bui K, Sostek M, Payza K, Eldon M. Floettmann E, et al. Among authors: payza k. J Pharmacol Exp Ther. 2017 May;361(2):280-291. doi: 10.1124/jpet.116.239061. Epub 2017 Mar 23. J Pharmacol Exp Ther. 2017. PMID: 28336575 Free PMC article.

5

Novel Dmt-Tic dipeptide analogues as selective delta-opioid receptor antagonists.

Pagé D, McClory A, Mischki T, Schmidt R, Butterworth J, St-Onge S, Labarre M, Payza K, Brown W. Pagé D, et al. Among authors: payza k. Bioorg Med Chem Lett. 2000 Jan 17;10(2):167-70. doi: 10.1016/s0960-894x(99)00652-6. Bioorg Med Chem Lett. 2000. PMID: 10673103

6

Novel C-terminus modifications of the Dmt-Tic motif: a new class of dipeptide analogues showing altered pharmacological profiles toward the opioid receptors.

Pagé D, Naismith A, Schmidt R, Coupal M, Labarre M, Gosselin M, Bellemare D, Payza K, Brown W. Pagé D, et al. Among authors: payza k. J Med Chem. 2001 Jul 19;44(15):2387-90. doi: 10.1021/jm015532k. J Med Chem. 2001. PMID: 11448220

7

New diarylmethylpiperazines as potent and selective nonpeptidic delta opioid receptor agonists with increased In vitro metabolic stability.

Plobeck N, Delorme D, Wei ZY, Yang H, Zhou F, Schwarz P, Gawell L, Gagnon H, Pelcman B, Schmidt R, Yue SY, Walpole C, Brown W, Zhou E, Labarre M, Payza K, St-Onge S, Kamassah A, Morin PE, Projean D, Ducharme J, Roberts E. Plobeck N, et al. Among authors: payza k. J Med Chem. 2000 Oct 19;43(21):3878-94. doi: 10.1021/jm000228x. J Med Chem. 2000. PMID: 11052793

8

N,N-Diethyl-4-(phenylpiperidin-4-ylidenemethyl)benzamide: a novel, exceptionally selective, potent delta opioid receptor agonist with oral bioavailability and its analogues.

Wei ZY, Brown W, Takasaki B, Plobeck N, Delorme D, Zhou F, Yang H, Jones P, Gawell L, Gagnon H, Schmidt R, Yue SY, Walpole C, Payza K, St-Onge S, Labarre M, Godbout C, Jakob A, Butterworth J, Kamassah A, Morin PE, Projean D, Ducharme J, Roberts E. Wei ZY, et al. Among authors: payza k. J Med Chem. 2000 Oct 19;43(21):3895-905. doi: 10.1021/jm000229p. J Med Chem. 2000. PMID: 11052794

9

Discovery of mu-opioid selective ligands derived from 1-aminotetralin scaffolds made via metal-catalyzed ring-opening reactions.

Dockendorff C, Jin S, Olsen M, Lautens M, Coupal M, Hodzic L, Spear N, Payza K, Walpole C, Tomaszewski MJ. Dockendorff C, et al. Among authors: payza k. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1228-32. doi: 10.1016/j.bmcl.2008.12.095. Epub 2008 Dec 30. Bioorg Med Chem Lett. 2009. PMID: 19168350

10

The glycine residue in cyclic lactam analogues of galanin(1-16)-NH2 is important for stabilizing an N-terminal helix.

Carpenter KA, Schmidt R, Yue SY, Hodzic L, Pou C, Payza K, Godbout C, Brown W, Roberts E. Carpenter KA, et al. Among authors: payza k. Biochemistry. 1999 Nov 16;38(46):15295-304. doi: 10.1021/bi991081i. Biochemistry. 1999. PMID: 10563815

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