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N,N-Diethyl-4-[(3-hydroxyphenyl)(piperidin-4-yl)amino] benzamide derivatives: the development of diaryl amino piperidines as potent delta opioid receptor agonists with in vivo anti-nociceptive activity in rodent models.
Jones P, Griffin AM, Gawell L, Lavoie R, Delorme D, Roberts E, Brown W, Walpole C, Xiao W, Boulet J, Labarre M, Coupal M, Butterworth J, St-Onge S, Hodzic L, Salois D. Jones P, et al. Bioorg Med Chem Lett. 2009 Nov 1;19(21):5994-8. doi: 10.1016/j.bmcl.2009.09.072. Epub 2009 Sep 22. Bioorg Med Chem Lett. 2009. PMID: 19800791
Potent and orally efficacious benzothiazole amides as TRPV1 antagonists.
Besidski Y, Brown W, Bylund J, Dabrowski M, Dautrey S, Harter M, Horoszok L, Hu Y, Johnson D, Johnstone S, Jones P, Leclerc S, Kolmodin K, Kers I, Labarre M, Labrecque D, Laird J, Lundström T, Martino J, Maudet M, Munro A, Nylöf M, Penwell A, Rotticci D, Slaitas A, Sundgren-Andersson A, Svensson M, Terp G, Villanueva H, Walpole C, Zemribo R, Griffin AM. Besidski Y, et al. Among authors: griffin am. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6205-11. doi: 10.1016/j.bmcl.2012.08.018. Epub 2012 Aug 14. Bioorg Med Chem Lett. 2012. PMID: 22939234
Discovery of spirofused piperazine and diazepane amides as selective histamine-3 antagonists with in vivo efficacy in a mouse model of cognition.
Brown DG, Bernstein PR, Griffin A, Wesolowski S, Labrecque D, Tremblay MC, Sylvester M, Mauger R, Edwards PD, Throner SR, Folmer JJ, Cacciola J, Scott C, Lazor LA, Pourashraf M, Santhakumar V, Potts WM, Sydserff S, Giguère P, Lévesque C, Dasser M, Groblewski T. Brown DG, et al. Among authors: griffin a. J Med Chem. 2014 Feb 13;57(3):733-58. doi: 10.1021/jm4014828. Epub 2014 Jan 27. J Med Chem. 2014. PMID: 24410637
Strategies to improve in vivo toxicology outcomes for basic candidate drug molecules.
Luker T, Alcaraz L, Chohan KK, Blomberg N, Brown DS, Butlin RJ, Elebring T, Griffin AM, Guile S, St-Gallay S, Swahn BM, Swallow S, Waring MJ, Wenlock MC, Leeson PD. Luker T, et al. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5673-9. doi: 10.1016/j.bmcl.2011.07.074. Epub 2011 Jul 27. Bioorg Med Chem Lett. 2011. PMID: 21852131
Identifying consensus and areas for future research in chondrosarcoma : a report from the Birmingham Orthopaedic Oncology Meeting.
Jeys LM, Morris GV, Kurisunkal VJ, Botello E, Boyle RA, Ebeid W, Houdek MT, Puri A, Ruggieri P, Brennan B; BOOM Consensus Meeting Participants; Laitinen MK, Abad Repiso S, Abdelbary H, Abiad Mejia A, Abood AA, Abril Martin JC, Abudu A, Abu Elhamd A, Acosta M, Ae K, Agarwal M, Ajit Singh V, Akiyama T, Alshaygy I, Albergo JI, Alexander J, Alfaro PA, Alpan B, Amaya-Valero J, Anderson M, Andreou D, Annabell L, Anthony C, Aoude A, Arteagoitia-Colino I, Asavamongkolkul A, Aston W, Asua Mentxaka L, Azzopardi C, Baad-Hansen T, Badr IT, Baixauli-Garcia F, Baker G, Balach T, Baldi GG, Barry J, Basile G, Bastoni S, Basuki M, Bauer H, Bayliss L, Becker RG, Bedi A, Benevenia J, Bengoa F, Bergh P, Bergovec M, Bernthal N, Binitie O, Boddie D, Boffano M, Bonilla Huertas P, Borgognoni AB, Botchu R, Bramer J, Brar R, Branford-White H, Broekhuis D, Broida SE, Budny T, Burke ZD, Cabrolier J, Calvo-Haro JA, Calvo Tapies JR, Cardoso R, Carey Smith R, Carvallo PI, Casales Fresenga N, Casanova JM, Ceballos O, Cebrian Parra JL, Chacon Cartaya S, Chan CM, Cho YJ, Choong P, Chung YG, Ciechanowicz D, Clara-Altamirano MA, Clever D, Colina SM, Consuegra L, Couch C, Cribb G, Cuervo C, Cusick LA, Dadia S, Dagher… See abstract for full author list ➔ Jeys LM, et al. Among authors: griffin a. Bone Joint J. 2025 Feb 1;107-B(2):246-252. doi: 10.1302/0301-620X.107B2.BJJ-2024-0643.R1. Bone Joint J. 2025. PMID: 39889743
1,383 results