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Targeting of a platinum-bound sunitinib analog to renal proximal tubular cells.
Dolman ME, Harmsen S, Pieters EH, Sparidans RW, Lacombe M, Szokol B, Orfi L, Kéri G, Storm G, Hennink WE, Kok RJ. Dolman ME, et al. Among authors: lacombe m. Int J Nanomedicine. 2012;7:417-33. doi: 10.2147/IJN.S26485. Epub 2012 Jan 31. Int J Nanomedicine. 2012. PMID: 22334775 Free PMC article.
Renal targeting of kinase inhibitors.
Dolman ME, Fretz MM, Segers GJ, Lacombe M, Prakash J, Storm G, Hennink WE, Kok RJ. Dolman ME, et al. Among authors: lacombe m. Int J Pharm. 2008 Dec 8;364(2):249-57. doi: 10.1016/j.ijpharm.2008.04.040. Epub 2008 May 4. Int J Pharm. 2008. PMID: 18550305 Review.
Intracellular delivery of the p38 mitogen-activated protein kinase inhibitor SB202190 [4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)1H-imidazole] in renal tubular cells: a novel strategy to treat renal fibrosis.
Prakash J, Sandovici M, Saluja V, Lacombe M, Schaapveld RQ, de Borst MH, van Goor H, Henning RH, Proost JH, Moolenaar F, Këri G, Meijer DK, Poelstra K, Kok RJ. Prakash J, et al. Among authors: lacombe m. J Pharmacol Exp Ther. 2006 Oct;319(1):8-19. doi: 10.1124/jpet.106.106054. Epub 2006 Jun 28. J Pharmacol Exp Ther. 2006. PMID: 16807361
Delivery of the p38 MAPkinase inhibitor SB202190 to angiogenic endothelial cells: development of novel RGD-equipped and PEGylated drug-albumin conjugates using platinum(II)-based drug linker technology.
Temming K, Lacombe M, van der Hoeven P, Prakash J, Gonzalo T, Dijkers EC, Orfi L, Kéri G, Poelstra K, Molema G, Kok RJ. Temming K, et al. Among authors: lacombe m. Bioconjug Chem. 2006 Sep-Oct;17(5):1246-55. doi: 10.1021/bc0600158. Bioconjug Chem. 2006. PMID: 16984135
Local inhibition of liver fibrosis by specific delivery of a platelet-derived growth factor kinase inhibitor to hepatic stellate cells.
Gonzalo T, Beljaars L, van de Bovenkamp M, Temming K, van Loenen AM, Reker-Smit C, Meijer DK, Lacombe M, Opdam F, Kéri G, Orfi L, Poelstra K, Kok RJ. Gonzalo T, et al. Among authors: lacombe m. J Pharmacol Exp Ther. 2007 Jun;321(3):856-65. doi: 10.1124/jpet.106.114496. Epub 2007 Mar 16. J Pharmacol Exp Ther. 2007. PMID: 17369283
494 results