Venot C - Search Results

1

Discovery of the first non-ATP competitive IGF-1R kinase inhibitors: advantages in comparison with competitive inhibitors.

Lesuisse D, Mauger J, Nemecek C, Maignan S, Boiziau J, Harlow G, Hittinger A, Ruf S, Strobel H, Nair A, Ritter K, Malleron JL, Dagallier A, El-Ahmad Y, Guilloteau JP, Guizani H, Bouchard H, Venot C. Lesuisse D, et al. Among authors: venot c. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2224-8. doi: 10.1016/j.bmcl.2011.03.003. Epub 2011 Mar 4. Bioorg Med Chem Lett. 2011. PMID: 21441024

2

Design of potent IGF1-R inhibitors related to bis-azaindoles.

Nemecek C, Metz WA, Wentzler S, Ding FX, Venot C, Souaille C, Dagallier A, Maignan S, Guilloteau JP, Bernard F, Henry A, Grapinet S, Lesuisse D. Nemecek C, et al. Among authors: venot c. Chem Biol Drug Des. 2010 Aug;76(2):100-6. doi: 10.1111/j.1747-0285.2010.00991.x. Epub 2010 Jun 9. Chem Biol Drug Des. 2010. PMID: 20545947

3

CD45neg but not CD45pos human myeloma cells are sensitive to the inhibition of IGF-1 signaling by a murine anti-IGF-1R monoclonal antibody, mAVE1642.

Descamps G, Wuillème-Toumi S, Trichet V, Venot C, Debussche L, Hercend T, Collette M, Robillard N, Bataille R, Amiot M. Descamps G, et al. Among authors: venot c. J Immunol. 2006 Sep 15;177(6):4218-23. doi: 10.4049/jimmunol.177.6.4218. J Immunol. 2006. PMID: 16951388

4

The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression.

Venot C, Maratrat M, Dureuil C, Conseiller E, Bracco L, Debussche L. Venot C, et al. EMBO J. 1998 Aug 17;17(16):4668-79. doi: 10.1093/emboj/17.16.4668. EMBO J. 1998. PMID: 9707426 Free PMC article.

5

A humanised anti-IGF-1R monoclonal antibody (AVE1642) enhances Bortezomib-induced apoptosis in myeloma cells lacking CD45.

Descamps G, Gomez-Bougie P, Venot C, Moreau P, Bataille R, Amiot M. Descamps G, et al. Among authors: venot c. Br J Cancer. 2009 Jan 27;100(2):366-9. doi: 10.1038/sj.bjc.6604839. Br J Cancer. 2009. PMID: 19165200 Free PMC article.

6

Anti-insulin-like growth factor 1 receptor antibody EM164 (murine AVE1642) exhibits anti-tumour activity alone and in combination with temozolomide against neuroblastoma.

Geoerger B, Brasme JF, Daudigeos-Dubus E, Opolon P, Venot C, Debussche L, Vrignaud P, Vassal G. Geoerger B, et al. Among authors: venot c. Eur J Cancer. 2010 Dec;46(18):3251-62. doi: 10.1016/j.ejca.2010.06.005. Epub 2010 Jun 28. Eur J Cancer. 2010. PMID: 20591650

7

CTS1: a p53-derived chimeric tumor suppressor gene with enhanced in vitro apoptotic properties.

Conseiller E, Debussche L, Landais D, Venot C, Maratrat M, Sierra V, Tocque B, Bracco L. Conseiller E, et al. Among authors: venot c. J Clin Invest. 1998 Jan 1;101(1):120-7. doi: 10.1172/JCI1140. J Clin Invest. 1998. PMID: 9421473 Free PMC article.

8

Restoration of transcriptional activity of p53 mutants in human tumour cells by intracellular expression of anti-p53 single chain Fv fragments.

Caron de Fromentel C, Gruel N, Venot C, Debussche L, Conseiller E, Dureuil C, Teillaud JL, Tocque B, Bracco L. Caron de Fromentel C, et al. Among authors: venot c. Oncogene. 1999 Jan 14;18(2):551-7. doi: 10.1038/sj.onc.1202338. Oncogene. 1999. PMID: 9927212

9

A tumor specific single chain antibody dependent gene expression system.

Mary MN, Venot C, Caron de Fromentel C, Debussche L, Conseiller E, Cochet O, Gruel N, Teillaud JL, Schweighoffer F, Tocque B, Bracco L. Mary MN, et al. Among authors: venot c. Oncogene. 1999 Jan 14;18(2):559-64. doi: 10.1038/sj.onc.1202377. Oncogene. 1999. PMID: 9927213

10

Definition of a p53 transactivation function-deficient mutant and characterization of two independent p53 transactivation subdomains.

Venot C, Maratrat M, Sierra V, Conseiller E, Debussche L. Venot C, et al. Oncogene. 1999 Apr 8;18(14):2405-10. doi: 10.1038/sj.onc.1202539. Oncogene. 1999. PMID: 10327062

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