Hsieh HP - Search Results

1

Scaffold-hopping strategy: synthesis and biological evaluation of 5,6-fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents.

Tung YS, Coumar MS, Wu YS, Shiao HY, Chang JY, Liou JP, Shukla P, Chang CW, Chang CY, Kuo CC, Yeh TK, Lin CY, Wu JS, Wu SY, Liao CC, Hsieh HP. Tung YS, et al. Among authors: hsieh hp. J Med Chem. 2011 Apr 28;54(8):3076-80. doi: 10.1021/jm101027s. Epub 2011 Mar 24. J Med Chem. 2011. PMID: 21434659

2

Synthesis and structure-activity relationship of 2-aminobenzophenone derivatives as antimitotic agents.

Liou JP, Chang CW, Song JS, Yang YN, Yeh CF, Tseng HY, Lo YK, Chang YL, Chang CM, Hsieh HP. Liou JP, et al. Among authors: hsieh hp. J Med Chem. 2002 Jun 6;45(12):2556-62. doi: 10.1021/jm010365+. J Med Chem. 2002. PMID: 12036364

3

Structure-activity and crystallographic analysis of benzophenone derivatives-the potential anticancer agents.

Hsieh HP, Liou JP, Lin YT, Mahindroo N, Chang JY, Yang YN, Chern SS, Tan UK, Chang CW, Chen TW, Lin CH, Chang YY, Wang CC. Hsieh HP, et al. Bioorg Med Chem Lett. 2003 Jan 6;13(1):101-5. doi: 10.1016/s0960-894x(02)00850-8. Bioorg Med Chem Lett. 2003. PMID: 12467626

4

Dual inhibition of topoisomerase I and tubulin polymerization by BPR0Y007, a novel cytotoxic agent.

Chang JY, Hsieh HP, Pan WY, Liou JP, Bey SJ, Chen LT, Liu JF, Song JS. Chang JY, et al. Among authors: hsieh hp. Biochem Pharmacol. 2003 Jun 15;65(12):2009-19. doi: 10.1016/s0006-2952(03)00197-7. Biochem Pharmacol. 2003. PMID: 12787881

5

Synthesis and structure-activity relationships of 3-aminobenzophenones as antimitotic agents.

Liou JP, Chang JY, Chang CW, Chang CY, Mahindroo N, Kuo FM, Hsieh HP. Liou JP, et al. Among authors: hsieh hp. J Med Chem. 2004 May 20;47(11):2897-905. doi: 10.1021/jm0305974. J Med Chem. 2004. PMID: 15139768

6

A novel bis-benzylidenecyclopentanone derivative, BPR0Y007, inducing a rapid caspase activation involving upregulation of Fas (CD95/APO-1) and wild-type p53 in human oral epidermoid carcinoma cells.

Juang SH, Pan WY, Kuo CC, Liou JP, Hung YM, Chen LT, Hsieh HP, Chang JY. Juang SH, et al. Among authors: hsieh hp. Biochem Pharmacol. 2004 Jul 15;68(2):293-303. doi: 10.1016/j.bcp.2004.03.036. Biochem Pharmacol. 2004. PMID: 15194001

7

BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo.

Kuo CC, Hsieh HP, Pan WY, Chen CP, Liou JP, Lee SJ, Chang YL, Chen LT, Chen CT, Chang JY. Kuo CC, et al. Among authors: hsieh hp. Cancer Res. 2004 Jul 1;64(13):4621-8. doi: 10.1158/0008-5472.CAN-03-3474. Cancer Res. 2004. PMID: 15231674

8

Concise synthesis and structure-activity relationships of combretastatin A-4 analogues, 1-aroylindoles and 3-aroylindoles, as novel classes of potent antitubulin agents.

Liou JP, Chang YL, Kuo FM, Chang CW, Tseng HY, Wang CC, Yang YN, Chang JY, Lee SJ, Hsieh HP. Liou JP, et al. Among authors: hsieh hp. J Med Chem. 2004 Aug 12;47(17):4247-57. doi: 10.1021/jm049802l. J Med Chem. 2004. PMID: 15293996

9

Pharmaceutical design of antimitotic agents based on combretastatins.

Hsieh HP, Liou JP, Mahindroo N. Hsieh HP, et al. Curr Pharm Des. 2005;11(13):1655-77. doi: 10.2174/1381612053764751. Curr Pharm Des. 2005. PMID: 15892667 Review.

10

Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system.

Hwang DR, Wu YS, Chang CW, Lien TW, Chen WC, Tan UK, Hsu JT, Hsieh HP. Hwang DR, et al. Among authors: hsieh hp. Bioorg Med Chem. 2006 Jan 1;14(1):83-91. doi: 10.1016/j.bmc.2005.07.055. Epub 2005 Sep 2. Bioorg Med Chem. 2006. PMID: 16140536

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