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Filaggrin null mutations are not a protective factor for acne vulgaris.
Common JE, Brown SJ, Haines RL, Goh CS, Chen H, Balakrishnan A, Munro CS, Tan AW, Tan HH, Tang MB, Lane EB. Common JE, et al. Among authors: chen h. J Invest Dermatol. 2011 Jun;131(6):1378-80. doi: 10.1038/jid.2011.23. Epub 2011 Feb 17. J Invest Dermatol. 2011. PMID: 21326297 Free PMC article. No abstract available.
Validation of GWAS loci for atopic dermatitis in a Singapore Chinese population.
Andiappan AK, Foo JN, Choy MW, Chen H, Common JE, Tang MB, van Bever HP, Giam YC, Suri BK, Ramani A, Nilkanth PP, Lane EB, Wang de Y, Chew FT, Liu J. Andiappan AK, et al. Among authors: chen h. J Invest Dermatol. 2012 May;132(5):1505-7. doi: 10.1038/jid.2011.471. Epub 2012 Feb 9. J Invest Dermatol. 2012. PMID: 22318392 Free article. No abstract available.
Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency.
Kezic S, O'Regan GM, Lutter R, Jakasa I, Koster ES, Saunders S, Caspers P, Kemperman PM, Puppels GJ, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Fallon PG, McLean WH, Irvine AD. Kezic S, et al. Among authors: chen h. J Allergy Clin Immunol. 2012 Apr;129(4):1031-9.e1. doi: 10.1016/j.jaci.2011.12.989. Epub 2012 Feb 8. J Allergy Clin Immunol. 2012. PMID: 22322004 Free PMC article.
Array-based sequencing of filaggrin gene for comprehensive detection of disease-associated variants.
Wong XFCC, Denil SLIJ, Foo JN, Chen H, Tay ASL, Haines RL, Tang MBY, McLean WHI, Sandilands A, Smith FJD, Lane EB, Liu J, Common JEA. Wong XFCC, et al. Among authors: chen h. J Allergy Clin Immunol. 2018 Feb;141(2):814-816. doi: 10.1016/j.jaci.2017.10.001. Epub 2017 Oct 19. J Allergy Clin Immunol. 2018. PMID: 29056476 Free PMC article. No abstract available.
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