Geng M - Search Results

1

Synthesis and c-Met kinase inhibition of 3,5-disubstituted and 3,5,7-trisubstituted quinolines: identification of 3-(4-acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-7- (trifluoromethyl)quinoline as a novel anticancer agent.

Wang Y, Ai J, Wang Y, Chen Y, Wang L, Liu G, Geng M, Zhang A. Wang Y, et al. Among authors: geng m. J Med Chem. 2011 Apr 14;54(7):2127-42. doi: 10.1021/jm101340q. Epub 2011 Mar 15. J Med Chem. 2011. PMID: 21405128

2

Sulfated polymannuroguluronate, a novel anti-acquired immune deficiency syndrome drug candidate, blocks neuroinflammatory signalling by targeting the transactivator of transcription (Tat) protein.

Hui B, Xia W, Li J, Wang L, Ai J, Geng M. Hui B, et al. Among authors: geng m. J Neurochem. 2006 Apr;97(2):334-44. doi: 10.1111/j.1471-4159.2006.03698.x. Epub 2006 Mar 15. J Neurochem. 2006. PMID: 16539678 Free article.

3

Oligomannurarate sulfate, a novel heparanase inhibitor simultaneously targeting basic fibroblast growth factor, combats tumor angiogenesis and metastasis.

Zhao H, Liu H, Chen Y, Xin X, Li J, Hou Y, Zhang Z, Zhang X, Xie C, Geng M, Ding J. Zhao H, et al. Among authors: geng m. Cancer Res. 2006 Sep 1;66(17):8779-87. doi: 10.1158/0008-5472.CAN-06-1382. Cancer Res. 2006. PMID: 16951194

4

R16, a novel amonafide analogue, induces apoptosis and G2-M arrest via poisoning topoisomerase II.

Zhu H, Huang M, Yang F, Chen Y, Miao ZH, Qian XH, Xu YF, Qin YX, Luo HB, Shen X, Geng MY, Cai YJ, Ding J. Zhu H, et al. Among authors: geng my. Mol Cancer Ther. 2007 Feb;6(2):484-95. doi: 10.1158/1535-7163.MCT-06-0584. Mol Cancer Ther. 2007. PMID: 17308047

5

MFTZ-1, an actinomycetes subspecies derived antitumor macrolide, functions as a novel topoisomerase II poison.

Xie CY, Zhu H, Lin LP, Miao ZH, Geng MY, Cai YJ, Chen Y, Zhao HJ, Luo HB, Zhang XW, Fan LM, Shen YM, Ding J. Xie CY, et al. Mol Cancer Ther. 2007 Nov;6(11):3059-70. doi: 10.1158/1535-7163.MCT-07-0014. Mol Cancer Ther. 2007. PMID: 18025289

6

Naturally occurring homoisoflavonoids function as potent protein tyrosine kinase inhibitors by c-Src-based high-throughput screening.

Lin LG, Xie H, Li HL, Tong LJ, Tang CP, Ke CQ, Liu QF, Lin LP, Geng MY, Jiang H, Zhao WM, Ding J, Ye Y. Lin LG, et al. J Med Chem. 2008 Aug 14;51(15):4419-29. doi: 10.1021/jm701501x. Epub 2008 Jul 9. J Med Chem. 2008. PMID: 18610999

7

alpha2,6-hyposialylation of c-Met abolishes cell motility of ST6Gal-I-knockdown HCT116 cells.

Qian J, Zhu CH, Tang S, Shen AJ, Ai J, Li J, Geng MY, Ding J. Qian J, et al. Acta Pharmacol Sin. 2009 Jul;30(7):1039-45. doi: 10.1038/aps.2009.84. Epub 2009 Jun 1. Acta Pharmacol Sin. 2009. PMID: 19483716 Free PMC article.

8

Marine-derived oligosaccharide sulfate (JG3) suppresses heparanase-driven cell adhesion events in heparanase over-expressing CHO-K1 cells.

Li QN, Liu HY, Xin XL, Pan QM, Wang L, Zhang J, Chen Q, Geng MY, Ding J. Li QN, et al. Acta Pharmacol Sin. 2009 Jul;30(7):1033-8. doi: 10.1038/aps.2009.97. Epub 2009 Jun 22. Acta Pharmacol Sin. 2009. PMID: 19543297 Free PMC article.

9

Trigochilides A and B, two highly modified daphnane-type diterpenoids from Trigonostemon chinensis.

Chen HD, He XF, Ai J, Geng MY, Yue JM. Chen HD, et al. Org Lett. 2009 Sep 17;11(18):4080-3. doi: 10.1021/ol901506x. Org Lett. 2009. PMID: 19702252

10

Trigochinins A-C: three new daphnane-type diterpenes from Trigonostemon chinensis.

Chen HD, Yang SP, He XF, Ai J, Liu ZK, Liu HB, Geng MY, Yue JM. Chen HD, et al. Org Lett. 2010 Mar 19;12(6):1168-71. doi: 10.1021/ol9028995. Org Lett. 2010. PMID: 20148570

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